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    MTK S-methyl-5-thioribose kinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841405, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MTK
    Official Full Name
    S-methyl-5-thioribose kinase
    Primary source
    TAIR:AT1G49820
    Locus tag
    AT1G49820
    See related
    Araport:AT1G49820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    5-methylthioribose kinase 1; ATMTK; F10F5.1; F10F5_1; MTK1; S-methyl-5-thioribose kinase
    Summary
    encodes 5-methylthioribose kinase, involved in methionine cycle
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    Genomic context

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    See MTK in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (18442882..18445350)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Na+/H+ antiporter 2 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA Neighboring gene glutamyl-tRNA (Gln) amidotransferase subunit A (DUF620)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of Arabidopsis thaliana 5-methylthioribose kinase reveals a more occluded active site than its bacterial homolog. Ku SY, et al. BMC Struct Biol, 2007 Oct 25. PMID 17961230, Free PMC Article
    2. Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis. Pommerrenig B, et al. Plant Cell, 2011 May. PMID 21540433, Free PMC Article
    3. Functional analysis of methylthioribose kinase genes in plants. Sauter M, et al. Plant Physiol, 2004 Dec. PMID 15557090, Free PMC Article
    4. The role of methionine recycling for ethylene synthesis in Arabidopsis. Bürstenbinder K, et al. Plant J, 2007 Jan. PMID 17144895
    5. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_103869.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-methyl-5-thioribose kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables S-methyl-5-thioribose kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables S-methyl-5-thioribose kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-methionine salvage from methylthioadenosine TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    S-methyl-5-thioribose kinase
    NP_564555.1
    • S-methyl-5-thioribose kinase (MTK); CONTAINS InterPro DOMAIN/s: Methylthioribose kinase (InterPro:IPR009212), Aminoglycoside phosphotransferase (InterPro:IPR002575), Protein kinase-like domain (InterPro:IPR011009); Has 954 Blast hits to 954 proteins in 299 species: Archae - 0; Bacteria - 750; Metazoa - 4; Fungi - 0; Plants - 63; Viruses - 0; Other Eukaryotes - 137 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18442882..18445350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103869.4 → NP_564555.1  S-methyl-5-thioribose kinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564555.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C6D2
      UniProtKB/TrEMBL
      A0A178WLE1, A0A5S9WQC0
      Conserved Domains (1) summary
      PLN02756
      Location:1 → 420
      PLN02756; S-methyl-5-thioribose kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C6D2.1

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