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    Glycine cleavage T-protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842391, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Glycine cleavage T-protein family
    Primary source
    TAIR:AT1G60990
    Locus tag
    AT1G60990
    See related
    Araport:AT1G60990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T7P1.13; T7P1_13
    Summary
    Encodes a chloroplast-localized COG0354 protein that requires folate for its function in Fe/S cluster biogenesis.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (22462026..22465495, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene SCR-like 4 Neighboring gene SCR-like 5 Neighboring gene SCR-like 7 Neighboring gene S3 self-incompatibility locus-linked pollen protein Neighboring gene kinetochore protein Neighboring gene cleavage and polyadenylation specificity factor 73-I

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial and plastidial COG0354 proteins have folate-dependent functions in iron-sulphur cluster metabolism. Waller JC, et al. J Exp Bot, 2012 Jan. PMID 21984653, Free PMC Article
    2. A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life. Waller JC, et al. Proc Natl Acad Sci U S A, 2010 Jun 8. PMID 20489182, Free PMC Article
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    NM_001084279.1
    NM_001124050.2
    NM_104780.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Glycine cleavage T-protein family
    NP_001077748.1
    • Glycine cleavage T-protein family; FUNCTIONS IN: aminomethyltransferase activity; INVOLVED IN: glycine catabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Folate-binding, YgfZ (InterPro:IPR017703), Glycine cleavage T-protein, N-terminal (InterPro:IPR006222), Glycine cleavage T-protein, C-terminal barrel (InterPro:IPR013977); BEST Arabidopsis thaliana protein match is: Glycine cleavage T-protein family (TAIR:AT1G11860.3); Has 8503 Blast hits to 8501 proteins in 1606 species: Archae - 129; Bacteria - 4545; Metazoa - 161; Fungi - 80; Plants - 109; Viruses - 0; Other Eukaryotes - 3479 (source: NCBI BLink).
    NP_001117522.1
    • Glycine cleavage T-protein family; FUNCTIONS IN: aminomethyltransferase activity; INVOLVED IN: glycine catabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Folate-binding, YgfZ (InterPro:IPR017703), Glycine cleavage T-protein, N-terminal (InterPro:IPR006222), Glycine cleavage T-protein, C-terminal barrel (InterPro:IPR013977); BEST Arabidopsis thaliana protein match is: Glycine cleavage T-protein family (TAIR:AT1G11860.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_176295.3
    • Glycine cleavage T-protein family; FUNCTIONS IN: aminomethyltransferase activity; INVOLVED IN: glycine catabolic process, glycine decarboxylation via glycine cleavage system; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Folate-binding, YgfZ (InterPro:IPR017703), Glycine cleavage T-protein, N-terminal (InterPro:IPR006222), Glycine cleavage T-protein, C-terminal barrel (InterPro:IPR013977); BEST Arabidopsis thaliana protein match is: Glycine cleavage T-protein family (TAIR:AT1G11860.3); Has 8503 Blast hits to 8501 proteins in 1606 species: Archae - 129; Bacteria - 4545; Metazoa - 161; Fungi - 80; Plants - 109; Viruses - 0; Other Eukaryotes - 3479 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22462026..22465495 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001124050.2 → NP_001117522.1  Glycine cleavage T-protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117522.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q681Y3, Q6NKY4, Q9C954
      UniProtKB/TrEMBL
      A0A178W8G5, A0A5S9WRE0
      Conserved Domains (1) summary
      COG0354
      Location:111 → 429
      YgfZ; Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification [Posttranslational modification, protein turnover, chaperones]

    2. NM_001084279.1 → NP_001077748.1  Glycine cleavage T-protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077748.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q681Y3, Q6NKY4, Q9C954
      UniProtKB/TrEMBL
      A0A178W8G5, A0A5S9WRE0
      Conserved Domains (1) summary
      COG0354
      Location:111 → 429
      YgfZ; Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification [Posttranslational modification, protein turnover, chaperones]

    3. NM_104780.4 → NP_176295.3  Glycine cleavage T-protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176295.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q681Y3, Q6NKY4, Q9C954
      UniProtKB/TrEMBL
      A0A178W8G5, A0A5S9WRE0
      Conserved Domains (1) summary
      COG0354
      Location:111 → 429
      YgfZ; Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q681Y3.1

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