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    LYM2 lysm domain GPI-anchored protein 2 precursor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816217, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LYM2
    Official Full Name
    lysm domain GPI-anchored protein 2 precursor
    Primary source
    TAIR:AT2G17120
    Locus tag
    AT2G17120
    See related
    Araport:AT2G17120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CEBiP-like 1; CL-1; F6P23.25; F6P23_25; LYP1; lysm domain GPI-anchored protein 2 precursor; lysM domain GPI-anchored protein 2 precursor; LysM-containing receptor protein 1
    Summary
    Induction of chitin-responsive genes by chitin treatment is not blocked in the mutant.
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    Genomic context

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    See LYM2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (7458930..7460819)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase subunit beta, putative (DUF630 and DUF632) Neighboring gene pseudo Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene isocitrate dehydrogenase subunit 2 Neighboring gene Plant regulator RWP-RK family protein Neighboring gene Interleukin-1 receptor-associated kinase 4 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LYM2-dependent chitin perception limits molecular flux via plasmodesmata. Faulkner C, et al. Proc Natl Acad Sci U S A, 2013 May 28. PMID 23674687, Free PMC Article
    2. Presence of LYM2 dependent but CERK1 independent disease resistance in Arabidopsis. Narusaka Y, et al. Plant Signal Behav, 2013 Sep. PMID 23803749, Free PMC Article
    3. Functional characterization of CEBiP and CERK1 homologs in arabidopsis and rice reveals the presence of different chitin receptor systems in plants. Shinya T, et al. Plant Cell Physiol, 2012 Oct. PMID 22891159
    4. LYK4, a lysin motif receptor-like kinase, is important for chitin signaling and plant innate immunity in Arabidopsis. Wan J, et al. Plant Physiol, 2012 Sep. PMID 22744984, Free PMC Article
    5. Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis. Borner GH, et al. Plant Physiol, 2003 Jun. PMID 12805588, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis CEBiP homolog, LYM2, is not involved in chitin signaling but contributes to CERK1 independent resistance against a fungal pathogen, Alternaria brassicicola.
      Title: Presence of LYM2 dependent but CERK1 independent disease resistance in Arabidopsis.
    2. LYM2 mediates a reduction in molecular flux via plasmodesmata in the presence of chitin.
      Title: LYM2-dependent chitin perception limits molecular flux via plasmodesmata.
    3. LYM2 showed a high-affinity binding for chitin oligosaccharides.
      Title: Functional characterization of CEBiP and CERK1 homologs in arabidopsis and rice reveals the presence of different chitin receptor systems in plants.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_127266.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    lysm domain GPI-anchored protein 2 precursor
    NP_565406.1
    • lysm domain GPI-anchored protein 2 precursor (LYM2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: cell wall macromolecule catabolic process; LOCATED IN: anchored to plasma membrane, plasma membrane, anchored to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidoglycan-binding lysin domain (InterPro:IPR018392), Peptidoglycan-binding Lysin subgroup (InterPro:IPR002482); BEST Arabidopsis thaliana protein match is: lysm domain GPI-anchored protein 1 precursor (TAIR:AT1G21880.2); Has 636 Blast hits to 591 proteins in 145 species: Archae - 0; Bacteria - 285; Metazoa - 0; Fungi - 0; Plants - 336; Viruses - 0; Other Eukaryotes - 15 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7458930..7460819
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127266.4 → NP_565406.1  lysm domain GPI-anchored protein 2 precursor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565406.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23006, Q8L9K9
      UniProtKB/TrEMBL
      A0A178VYE4, A0A5S9WYL4, A0A7G2ECU7
      Conserved Domains (2) summary
      PRK11198
      Location:110 → 156
      PRK11198; LysM domain/BON superfamily protein; Provisional
      pfam01476
      Location:174 → 217
      LysM; LysM domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23006.1

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