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    zinc ion binding protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838472, updated on 18-Sep-2024

    Summary

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    Official Full Name
    zinc ion binding protein
    Primary source
    TAIR:AT1G18910
    Locus tag
    AT1G18910
    See related
    Araport:AT1G18910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14D16.31; F14D16_31
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (6532559..6538145, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene ncRNA Neighboring gene calcium-dependent protein kinase 1 Neighboring gene ncRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene pseudo Neighboring gene Nodulin-like / Major Facilitator Superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BRUTUS-LIKE (BTSL) E3 ligase-mediated fine-tuning of Fe regulation negatively affects Zn tolerance of Arabidopsis. Stanton C, et al. J Exp Bot, 2023 Sep 29. PMID 37393944, Free PMC Article
    2. Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling. Rodríguez-Celma J, et al. Proc Natl Acad Sci U S A, 2019 Aug 27. PMID 31413196, Free PMC Article
    3. The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response. Colangelo EP, et al. Plant Cell, 2004 Dec. PMID 15539473, Free PMC Article
    4. BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana. Hindt MN, et al. Metallomics, 2017 Jul 19. PMID 28620661, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the two A. thaliana BTS paralogs, BTS LIKE1 (BTSL1) and BTS LIKE2 (BTSL2) encode proteins that act redundantly as negative regulators of the iron deficiency response.[BTSL2]
      Title: BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_101748.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to iron ion starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to iron(II) ion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular iron ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within iron import into cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within iron ion import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of iron ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to iron ion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    zinc ion binding protein
    NP_173325.2
    • zinc ion binding;zinc ion binding; FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, CTCHY-type (InterPro:IPR017921), Zinc finger, CHY-type (InterPro:IPR008913), Zinc finger, RING-type (InterPro:IPR001841), Haemerythrin/HHE cation-binding motif (InterPro:IPR012312); BEST Arabidopsis thaliana protein match is: zinc ion binding (TAIR:AT1G74770.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6532559..6538145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101748.3 → NP_173325.2  zinc ion binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173325.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IDY5, Q67YB6, Q9LMD9
      UniProtKB/TrEMBL
      A0A178W596, A0A5S9V4J2, A0A654EB76
      Conserved Domains (4) summary
      cd12108
      Location:47 → 176
      Hr-like; Hemerythrin-like domain
      cd16464
      Location:1147 → 1190
      RING-H2_Pirh2; RING finger, H2 subclass, found in p53-induced RING-H2 protein (Pirh2) and similar proteins
      pfam05495
      Location:1020 → 1095
      zf-CHY; CHY zinc finger
      pfam14599
      Location:1194 → 1252
      zinc_ribbon_6; Zinc-ribbon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4IDY5.1

    Gene LinkOut

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