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    disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816210, updated on 18-Sep-2024

    Summary

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    Official Full Name
    disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT2G17050
    Locus tag
    AT2G17050
    See related
    Araport:AT2G17050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6P23.20; F6P23_20
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (7410704..7415802, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 36 Neighboring gene uncharacterized protein Neighboring gene Toll-Interleukin-Resistance (TIR) domain family protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    disease resistance protein (TIR-NBS-LRR class)
    NP_179297.2
    • disease resistance protein (TIR-NBS-LRR class), putative; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT4G19520.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7410704..7415802 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335535.1 → NP_001324491.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B096, A0A654ETH3

    2. NM_127260.2 → NP_179297.2  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179297.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ETH3, F4IMF0
      Conserved Domains (8) summary
      cd09293
      Location:463 → 636
      AMN1; Antagonist of mitotic exit network protein 1
      smart00255
      Location:1125 → 1262
      TIR; Toll - interleukin 1 - resistance
      COG4886
      Location:412 → 615
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:485 → 506
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:49 → 267
      NB-ARC; NB-ARC domain
      pfam07725
      Location:437 → 456
      LRR_3; Leucine Rich Repeat
      pfam12799
      Location:532 → 564
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:646 → 699
      LRR_8; Leucine rich repeat

    3. NM_001335536.1 → NP_001324492.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B090, A0A654ETH3
    Nucleotide Protein
    Heading Accession and Version

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