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    ISU3 ISCU-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825719, updated on 18-Sep-2024

    Summary

    Official Symbol
    ISU3
    Official Full Name
    ISCU-like 3
    Primary source
    TAIR:AT4G04080
    Locus tag
    AT4G04080
    See related
    Araport:AT4G04080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATISU3; ISCU-like 3; ISCU-LIKE 3; T24H24.11; T24H24_11
    Summary
    Encodes a mitochondrial protein similar to E.coli IscU. In bacteria, IscU is a scaffold protein accepting sulfur and iron to build a transient Fe-S cluster,which is subsequently transferred to a target apoprotein.
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    Genomic context

    See ISU3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (1963291..1964471)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene BTB/POZ domain-containing protein Neighboring gene pseudo

    General gene information

    NM_116646.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural molecule activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    NOT located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in cytosol HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ISCU-like 3
    NP_192317.1
    • ISCU-like 3 (ISU3); CONTAINS InterPro DOMAIN/s: NIF system FeS cluster assembly, NifU, N-terminal (InterPro:IPR002871), ISC system FeS cluster assembly, IscU scaffold (InterPro:IPR011339); BEST Arabidopsis thaliana protein match is: SufE/NifU family protein (TAIR:AT4G22220.1); Has 5467 Blast hits to 5467 proteins in 1987 species: Archae - 110; Bacteria - 3663; Metazoa - 148; Fungi - 152; Plants - 89; Viruses - 0; Other Eukaryotes - 1305 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1963291..1964471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116646.3NP_192317.1  ISCU-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192317.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81433
      UniProtKB/TrEMBL
      A0A178UUZ7, A0A5S9XQ26, A0A654FM09
      Conserved Domains (1) summary
      PRK11325
      Location:28152
      PRK11325; scaffold protein; Provisional