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    ABCI8 ATP binding cassette protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825814, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCI8
    Official Full Name
    ATP binding cassette protein 1
    Primary source
    TAIR:AT4G04770
    Locus tag
    AT4G04770
    See related
    Araport:AT4G04770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABC1; ARABIDOPSIS THALIANA NUCLEOSOME ASSEMBLY PROTEIN 1; ATABC1; ATNAP1; ATP binding cassette protein 1; ATP-binding cassette I8; LAF6; LONG AFTER FR; T4B21.16; T4B21_16
    Summary
    Encodes an iron-stimulated ATPase. A member of the NAP subfamily of ABC transporters. Involved in Fe-S cluster assembly. Similar to SufB. Involved in the regulation of iron homeostasis. Able to form homodimers. Interacts with AtNAP7 inside the chloroplast.
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    Genomic context

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    See ABCI8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (2427686..2429899, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Major facilitator superfamily protein Neighboring gene Major facilitator superfamily protein Neighboring gene zinc ion binding protein Neighboring gene mediator 21

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana. Nagane T, et al. Planta, 2010 Mar. PMID 20087600
    2. A plastidic ABC protein involved in intercompartmental communication of light signaling. Møller SG, et al. Genes Dev, 2001 Jan 1. PMID 11156608, Free PMC Article
    3. A truncated Arabidopsis NUCLEOSOME ASSEMBLY PROTEIN 1, AtNAP1;3T, alters plant growth responses to abscisic acid and salt in the Atnap1;3-2 mutant. Liu ZQ, et al. Mol Plant, 2009 Jul. PMID 19825649
    4. AtNAP1 represents an atypical SufB protein in Arabidopsis plastids. Xu XM, et al. J Biol Chem, 2005 Feb 25. PMID 15611066, Free PMC Article
    5. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana.
      Title: Involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana.
    2. Study uncovered AtNAP1 proteins as positive regulators and AtNAP1;3T as a negative regulator in ABA signaling pathways, providing a novel link of chromatin remodeling to hormonal and stress responses.
      Title: A truncated Arabidopsis NUCLEOSOME ASSEMBLY PROTEIN 1, AtNAP1;3T, alters plant growth responses to abscisic acid and salt in the Atnap1;3-2 mutant.
    3. results show that AtNAP1 is an iron-stimulated ATPase and is capable of forming homodimers, and suggest that AtNAP1 represents an atypical plastidic SufB-like protein important for Fe-S cluster assembly and for regulating iron homeostasis (AtNAP1)
      Title: AtNAP1 represents an atypical SufB protein in Arabidopsis plastids.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_116715.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATPase-coupled transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular iron ion homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular iron ion homeostasis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of response to red or far red light IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    ATP binding cassette protein 1
    NP_192386.1
    • ATP binding cassette protein 1 (ABC1); FUNCTIONS IN: protein binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity; INVOLVED IN: cellular iron ion homeostasis, regulation of response to red or far red light, iron-sulfur cluster assembly; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SUF system FeS cluster assembly, SufB (InterPro:IPR010231), SUF system FeS cluster assembly, SufBD (InterPro:IPR000825); BEST Arabidopsis thaliana protein match is: Stabilizer of iron transporter SufD superfamily protein (TAIR:AT5G44316.1); Has 12037 Blast hits to 11965 proteins in 1962 species: Archae - 330; Bacteria - 6550; Metazoa - 4; Fungi - 1; Plants - 99; Viruses - 0; Other Eukaryotes - 5053 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2427686..2429899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116715.5 → NP_192386.1  ATP binding cassette protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192386.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZS97
      UniProtKB/TrEMBL
      A0A178USK1, A0A5S9XRP1, A0A654FLU5, A0A7G2EV07
      Conserved Domains (1) summary
      PRK11814
      Location:85 → 557
      PRK11814; cysteine desulfurase activator complex subunit SufB; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZS97.1

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