NAGS2 N-acetyl-l-glutamate synthase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NAGS2
Official Full Name: N-acetyl-l-glutamate synthase 2
Primary source: TAIR:AT4G37670
Locus tag: AT4G37670
See related: Araport:AT4G37670
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F19F18.160; F19F18_160; N-acetyl-l-glutamate synthase 2
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Genomic context

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See NAGS2 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 9

Sequence:: Chromosome: 4; NC_003075.7 (17696059..17698991, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_119930.3

Supported by ESTs:

NM_202972.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables L-glutamate N-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables L-methionine N-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in L-arginine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: N-acetyl-l-glutamate synthase 2

NP_568032.1

N-acetyl-l-glutamate synthase 2 (NAGS2); FUNCTIONS IN: acetyl-CoA:L-glutamate N-acetyltransferase activity, N-acetyltransferase activity; INVOLVED IN: cellular amino acid biosynthetic process, arginine biosynthetic process, metabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), GCN5-related N-acetyltransferase (InterPro:IPR000182), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Amino-acid N-acetyltransferase (ArgA) (InterPro:IPR010167); BEST Arabidopsis thaliana protein match is: N-acetyl-l-glutamate synthase 1 (TAIR:AT2G22910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NP_974701.1

N-acetyl-l-glutamate synthase 2 (NAGS2); FUNCTIONS IN: acetyl-CoA:L-glutamate N-acetyltransferase activity, N-acetyltransferase activity; INVOLVED IN: cellular amino acid biosynthetic process, arginine biosynthetic process, metabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Amino-acid N-acetyltransferase (ArgA) (InterPro:IPR010167); BEST Arabidopsis thaliana protein match is: N-acetyl-l-glutamate synthase 1 (TAIR:AT2G22910.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

17696059..17698991 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_202972.5 → NP_974701.1 N-acetyl-l-glutamate synthase 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_974701.1

Status: REVIEWED

UniProtKB/Swiss-Prot

B5X4Z4

UniProtKB/TrEMBL

A0A178V1D0, A0A5S9XZK4

Conserved Domains (1) summary

PLN02825
Location:84 → 602

PLN02825; amino-acid N-acetyltransferase
NM_119930.3 → NP_568032.1 N-acetyl-l-glutamate synthase 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_568032.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178UZU2, F4JS51, Q9SZF9

Conserved Domains (3) summary

PLN02825
Location:84 → 541

PLN02825; amino-acid N-acetyltransferase

cd04237
Location:83 → 449

AAK_NAGS-ABP; AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an ...

cl17182
Location:457 → 541

NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate