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    UPS1 ureide permease 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814888, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UPS1
    Official Full Name
    ureide permease 1
    Primary source
    TAIR:AT2G03590
    Locus tag
    AT2G03590
    See related
    Araport:AT2G03590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATUPS1; F19B11.4; F19B11_4; ureide permease 1
    Summary
    Encodes a member of a class of allantoin transporters.
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    Genomic context

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    See UPS1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (1094702..1096976)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene F-box family protein-like protein Neighboring gene ureide permease 3 Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis. Desimone M, et al. Plant Cell, 2002 Apr. PMID 11971139, Free PMC Article
    2. UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil. Schmidt A, et al. J Biol Chem, 2004 Oct 22. PMID 15308648
    3. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UPS1 and UPS2 from Arabidopsis have roles in high affinity transport of uracil and 5-fluorouracil [UPS1]
      Title: UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001335192.1
    NM_126409.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables allantoin:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables uracil transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within allantoin transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pyrimidine nucleobase salvage TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in uracil transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ureide permease 1
    NP_565303.1
    • ureide permease 1 (UPS1); FUNCTIONS IN: allantoin uptake transmembrane transporter activity; INVOLVED IN: allantoin transport; LOCATED IN: endomembrane system; BEST Arabidopsis thaliana protein match is: ureide permease 2 (TAIR:AT2G03530.2); Has 283 Blast hits to 283 proteins in 80 species: Archae - 0; Bacteria - 139; Metazoa - 0; Fungi - 0; Plants - 116; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1094702..1096976
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126409.4 → NP_565303.1  ureide permease 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565303.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q058M8, Q0WP08, Q9ZPR7
      UniProtKB/TrEMBL
      A0A178VW66, A0A5S9WWV9
      Conserved Domains (1) summary
      pfam07168
      Location:41 → 385
      Ureide_permease; Ureide permease

    2. NM_001335192.1 → NP_001324930.1  ureide permease 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q058M8, Q0WP08, Q9ZPR7
      UniProtKB/TrEMBL
      A0A178VW66, A0A5S9WWV9
      Conserved Domains (1) summary
      pfam07168
      Location:41 → 385
      Ureide_permease; Ureide permease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZPR7.1

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