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    Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834889, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Actin-binding FH2 (formin homology 2) family protein
    Primary source
    TAIR:AT5G48360
    Locus tag
    AT5G48360
    See related
    Araport:AT5G48360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K23F3.8; K23F3_8
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (19595536..19598492)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene Thioesterase/thiol ester dehydrase-isomerase superfamily protein Neighboring gene thioglucoside glucosidase 3 Neighboring gene BAK1-interacting receptor-like kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata. Diao M, et al. Elife, 2018 Aug 16. PMID 30113309, Free PMC Article
    2. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
    3. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124211.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    colocalizes_with plasmodesma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Actin-binding FH2 (formin homology 2) family protein
    NP_199647.2
    • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: Actin-binding FH2 (formin homology 2) family protein (TAIR:AT3G07540.1); Has 2644 Blast hits to 2444 proteins in 226 species: Archae - 2; Bacteria - 35; Metazoa - 1274; Fungi - 135; Plants - 653; Viruses - 75; Other Eukaryotes - 470 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19595536..19598492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124211.3 → NP_199647.2  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199647.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GX37, Q9LK78
      UniProtKB/TrEMBL
      A0A5S9YCE2, A0A654G9P2
      Conserved Domains (1) summary
      pfam02181
      Location:430 → 774
      FH2; Formin Homology 2 Domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GX37.2

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