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    WYR inner centromere protein, ARK-binding region protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835676, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WYR
    Official Full Name
    inner centromere protein, ARK-binding region protein
    Primary source
    TAIR:AT5G55820
    Locus tag
    AT5G55820
    See related
    Araport:AT5G55820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MDF20.26; MDF20_26; WYRD
    Summary
    Encodes a plant ortholog of the inner centromere protein (INCENP), which is implicated in the control of chromosome segregation and cytokinesis in yeast and animals. Required for female gametophytic cell specification and seed development.
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    Genomic context

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    See WYR in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (22586287..22594135)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene nicotinate/nicotinamide mononucleotide adenyltransferase Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Female gametophytic cell specification and seed development require the function of the putative Arabidopsis INCENP ortholog WYRD. Kirioukhova O, et al. Development, 2011 Aug. PMID 21752930
    2. Functional Analysis of the Plant Chromosomal Passenger Complex. Komaki S, et al. Plant Physiol, 2020 Aug. PMID 32461300, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. WYR encodes a putative Arabidopsis ortholog of the inner centromere protein (INCENP) and plays a role during both gametophytic differentiation and postfertilization development. [WYRD]
      Title: Female gametophytic cell specification and seed development require the function of the putative Arabidopsis INCENP ortholog WYRD.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001345152.1
    NM_001345153.1
    NM_001345156.1
    NM_001345157.1
    NM_001345158.1
    NM_001345159.1
    NM_001345160.1
    NM_001345161.1
    NM_124964.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    inner centromere protein, ARK-binding region protein
    NP_200393.1
    • CONTAINS InterPro DOMAIN/s: Inner centromere protein, ARK-binding region (InterPro:IPR005635); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22586287..22594135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345154.1 → NP_001331529.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE52, A0A654GBT6

    2. NM_001345155.1 → NP_001331530.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE61, A0A654GBT6

    3. NM_124964.1 → NP_200393.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200393.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2FGF4, Q9FM57
      Conserved Domains (3) summary
      TIGR02794
      Location:1501 → 1678
      tolA_full; TolA protein
      pfam03941
      Location:1746 → 1777
      INCENP_ARK-bind; Inner centromere protein, ARK binding region
      cl23765
      Location:1602 → 1671
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    4. NM_001345156.1 → NP_001331531.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE57, A0A654GBT6

    5. NM_001345157.1 → NP_001331532.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE54, A0A7G2FGF4

    6. NM_001345158.1 → NP_001331533.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE62, A0A654GBT6

    7. NM_001345159.1 → NP_001331526.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE37, A0A654GBT6

    8. NM_001345160.1 → NP_001331527.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE37, A0A654GBT6

    9. NM_001345161.1 → NP_001331528.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2FGF4, G3GBK1

    10. NM_001345152.1 → NP_001331524.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE82, A0A654GBT6

    11. NM_001345153.1 → NP_001331525.1  inner centromere protein, ARK-binding region protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BE53, A0A7G2FGF4
    Nucleotide Protein
    Heading Accession and Version

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