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    Cysteine proteinases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836141, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Cysteine proteinases superfamily protein
    Primary source
    TAIR:AT5G60190
    Locus tag
    AT5G60190
    See related
    Araport:AT5G60190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15L12.8; F15L12_8
    Summary
    Encodes a protein that can cleave residues from the C-terminus of RUB1 to prepare it for conjugation to target proteins.
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (24234431..24236242)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RNA binding (RRM/RBD/RNP motifs) family protein Neighboring gene pumilio 19 Neighboring gene TARGET OF MONOPTEROS 6 Neighboring gene ROP interactive partner 5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis. Mergner J, et al. J Biol Chem, 2017 Mar 3. PMID 28096463, Free PMC Article
    2. DENEDDYLASE1 deconjugates NEDD8 from non-cullin protein substrates in Arabidopsis thaliana. Mergner J, et al. Plant Cell, 2015 Mar. PMID 25783028, Free PMC Article
    3. SUMO-conjugating and SUMO-deconjugating enzymes from Arabidopsis. Colby T, et al. Plant Physiol, 2006 Sep. PMID 16920872, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_125412.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables deNEDDylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cysteine proteinases superfamily protein
    NP_200827.1
    • Cysteine proteinases superfamily protein; FUNCTIONS IN: cysteine-type peptidase activity, NEDD8-specific protease activity; INVOLVED IN: proteolysis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: LP.04 four leaves visible, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24234431..24236242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125412.4 → NP_200827.1  Cysteine proteinases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200827.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LSS7
      UniProtKB/TrEMBL
      A0A178UMI3, A0A5S9YG75
      Conserved Domains (1) summary
      cl23802
      Location:31 → 190
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSS7.1

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