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    NDC1 NAD(P)H dehydrogenase C1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830775, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NDC1
    Official Full Name
    NAD(P)H dehydrogenase C1
    Primary source
    TAIR:AT5G08740
    Locus tag
    AT5G08740
    See related
    Araport:AT5G08740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    NAD(P)H dehydrogenase C1
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    Genomic context

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    See NDC1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (2848352..2851534, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene polyketide cyclase/dehydrase/lipid transporter Neighboring gene IBR domain-containing protein Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterisation of the trans-membrane nucleoporins GP210 and NDC1 in Arabidopsis thaliana. Collins PP, et al. Plant Sci, 2023 Jul. PMID 37116717
    2. A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis. Fatihi A, et al. Plant Cell, 2015 Jun. PMID 26023160, Free PMC Article
    3. Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. Eugeni Piller L, et al. Proc Natl Acad Sci U S A, 2011 Aug 23. PMID 21844348, Free PMC Article
    4. An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana. Wallström SV, et al. Plant Sci, 2012 Feb. PMID 22195593
    5. Characterization of mitochondrial alternative NAD(P)H dehydrogenases in Arabidopsis: intraorganelle location and expression. Elhafez D, et al. Plant Cell Physiol, 2006 Jan. PMID 16258072

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Characterisation of the trans-membrane nucleoporins GP210 and NDC1 in Arabidopsis thaliana.
      Title: Characterisation of the trans-membrane nucleoporins GP210 and NDC1 in Arabidopsis thaliana.
    2. The alternatively spliced 5' domain of NDC1 strongly influences the expression of the functionally unrelated ACTIN2, which is a common reference gene in Arabidopsis thaliana for quantitative RT-PCR.
      Title: An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana.
    3. NDC1 is required for normal plastochromanol-8 accumulation and is essential for vitamin K(1) production.
      Title: Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_120955.8

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD(P)H dehydrogenase (quinone) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phylloquinone biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastoglobule HDA PubMed 

    General protein information

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    Preferred Names
    NAD(P)H dehydrogenase C1
    NP_568205.6
    • NAD(P)H dehydrogenase C1 (NDC1); FUNCTIONS IN: NADH dehydrogenase activity, oxidoreductase activity, FAD binding; INVOLVED IN: oxidation reduction; LOCATED IN: intrinsic to mitochondrial inner membrane, cell wall, chloroplast, plastoglobule; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327); BEST Arabidopsis thaliana protein match is: alternative NAD(P)H dehydrogenase 2 (TAIR:AT2G29990.1); Has 10792 Blast hits to 10785 proteins in 2211 species: Archae - 358; Bacteria - 8162; Metazoa - 316; Fungi - 520; Plants - 321; Viruses - 0; Other Eukaryotes - 1115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2848352..2851534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120955.8 → NP_568205.6  NAD(P)H dehydrogenase C1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568205.6

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KCG9, Q6KC19, Q8GXR9, Q93ZN8, Q9C5A3
      Conserved Domains (2) summary
      COG1252
      Location:80 → 499
      Ndh; NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]
      cl21454
      Location:247 → 316
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version

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