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    VSR3 vacuolar sorting receptor 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815962, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VSR3
    Official Full Name
    vacuolar sorting receptor 3
    Primary source
    TAIR:AT2G14740
    Locus tag
    AT2G14740
    See related
    Araport:AT2G14740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATVSR3; binding protein of 80 kDa 2;2; BP80-2;2; T6B13.4; vaculolar sorting receptor 3; VACUOLAR SORTING RECEPTOR 2;2; VACUOLAR SORTING RECEPTOR 3; VSR2;2
    Summary
    Encodes a vacuolar sorting receptor that participates in vacuolar sorting in vegetative tissues and in seeds.
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    Genomic context

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    See VSR3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (6308683..6312726)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene vacuolar sorting receptor 4 Neighboring gene pseudo Neighboring gene APS kinase Neighboring gene Myb/SANT-like DNA-binding domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of Arabidopsis vacuolar sorting receptor 3 reveals a putative function in guard cells. Avila EL, et al. J Exp Bot, 2008. PMID 18436547
    2. An ER-localized form of PV72, a seed-specific vacuolar sorting receptor, interferes the transport of an NPIR-containing proteinase in Arabidopsis leaves. Watanabe E, et al. Plant Cell Physiol, 2004 Jan. PMID 14749481
    3. Functional identification of sorting receptors involved in trafficking of soluble lytic vacuolar proteins in vegetative cells of Arabidopsis. Lee Y, et al. Plant Physiol, 2013 Jan. PMID 23175753, Free PMC Article
    4. Functional specialization within the vacuolar sorting receptor family: VSR1, VSR3 and VSR4 sort vacuolar storage cargo in seeds and vegetative tissues. Zouhar J, et al. Plant J, 2010 Nov. PMID 20807215
    5. A family of Arabidopsis plasma membrane receptors presenting animal beta-integrin domains. Laval V, et al. Biochim Biophys Acta, 1999 Nov 16. PMID 10561538

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VSR1, VSR3, and VSR4 exhibit functional redundancy in their role for the vacuolar trafficking of soluble proteins in vegetative cells.
      Title: Functional identification of sorting receptors involved in trafficking of soluble lytic vacuolar proteins in vegetative cells of Arabidopsis.
    2. Findings show that VSR1, VSR3 and VSR4 participate in vacuolar sorting of VAC2 in vegetative tissues, and 12S globulins and 2S albumins in seeds, an activity that is essential for seedling germination vigor. [VSR3]
      Title: Functional specialization within the vacuolar sorting receptor family: VSR1, VSR3 and VSR4 sort vacuolar storage cargo in seeds and vegetative tissues.
    3. Loss of AtVSR3 protein caused the accumulation of nitric oxide and hydrogen peroxide, signalling molecules implicated in the regulation of stomatal opening and closing.
      Title: Expression analysis of Arabidopsis vacuolar sorting receptor 3 reveals a putative function in guard cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_127038.2
    NM_179624.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein targeting to vacuole IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to vacuole TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi cis cisterna HDA PubMed 
    part_of Golgi transport complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    vacuolar sorting receptor 3
    NP_179081.1
    • vaculolar sorting receptor 3 (VSR3); FUNCTIONS IN: calcium ion binding; INVOLVED IN: intracellular protein transport, protein targeting to vacuole; LOCATED IN: integral to plasma membrane, Golgi transport complex, membrane; EXPRESSED IN: callus, leaf; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), EGF-like calcium-binding, conserved site (InterPro:IPR018097), EGF-like (InterPro:IPR006210), Growth factor, receptor (InterPro:IPR009030), EGF-like region, conserved site (InterPro:IPR013032); BEST Arabidopsis thaliana protein match is: vacuolar sorting receptor 4 (TAIR:AT2G14720.2); Has 14459 Blast hits to 6347 proteins in 253 species: Archae - 2; Bacteria - 131; Metazoa - 13188; Fungi - 10; Plants - 479; Viruses - 0; Other Eukaryotes - 649 (source: NCBI BLink).
    NP_849955.1
    • vaculolar sorting receptor 3 (VSR3); FUNCTIONS IN: calcium ion binding; INVOLVED IN: intracellular protein transport, protein targeting to vacuole; LOCATED IN: integral to plasma membrane, Golgi transport complex, membrane; EXPRESSED IN: callus, leaf; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), EGF-like calcium-binding, conserved site (InterPro:IPR018097), EGF-like (InterPro:IPR006210), Growth factor, receptor (InterPro:IPR009030), EGF-like region, conserved site (InterPro:IPR013032); BEST Arabidopsis thaliana protein match is: vacuolar sorting receptor 4 (TAIR:AT2G14720.2); Has 14459 Blast hits to 6347 proteins in 253 species: Archae - 2; Bacteria - 131; Metazoa - 13188; Fungi - 10; Plants - 479; Viruses - 0; Other Eukaryotes - 649 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6308683..6312726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127038.2 → NP_179081.1  vacuolar sorting receptor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179081.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80977
      UniProtKB/TrEMBL
      A0A178VT51, A0A7G2E8F6
      Conserved Domains (3) summary
      smart00179
      Location:517 → 545
      EGF_CA; Calcium-binding EGF-like domain
      cd02125
      Location:51 → 178
      PA_VSR; Protease-associated (PA) domain-containing plant vacuolar sorting receptor (VSR). This group includes various PA domain-containing VSRs such as garden pea BP-80, pumpkin PV72, and various Arabidopsis VSRs including AtVSR1. In contrast to most eukaryotes, ...
      pfam12662
      Location:498 → 520
      cEGF; Complement Clr-like EGF-like

    2. NM_179624.2 → NP_849955.1  vacuolar sorting receptor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849955.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80977
      UniProtKB/TrEMBL
      A0A178VT51, A0A7G2E8F6
      Conserved Domains (3) summary
      smart00179
      Location:517 → 545
      EGF_CA; Calcium-binding EGF-like domain
      cd02125
      Location:51 → 178
      PA_VSR; Protease-associated (PA) domain-containing plant vacuolar sorting receptor (VSR). This group includes various PA domain-containing VSRs such as garden pea BP-80, pumpkin PV72, and various Arabidopsis VSRs including AtVSR1. In contrast to most eukaryotes, ...
      pfam12662
      Location:498 → 520
      cEGF; Complement Clr-like EGF-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80977.1

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