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    TPP thylakoid processing peptide [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817595, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TPP
    Official Full Name
    thylakoid processing peptide
    Primary source
    TAIR:AT2G30440
    Locus tag
    AT2G30440
    See related
    Araport:AT2G30440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    plastidic type I signal peptidase 2B; Plsp2B; T6B20.20; T6B20_20; thylakoid processing peptide
    Summary
    Encodes a thylakoidal processing peptidase that removes signal sequences from proteins synthesized in the cytoplasm and transported into the thylakoid lumen.
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    Genomic context

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    See TPP in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (12972682..12975542)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional diversification of thylakoidal processing peptidases in Arabidopsis thaliana. Hsu SC, et al. PLoS One, 2011. PMID 22087276, Free PMC Article
    2. Characterization of a cDNA encoding the thylakoidal processing peptidase from Arabidopsis thaliana. Implications for the origin and catalytic mechanism of the enzyme. Chaal BK, et al. J Biol Chem, 1998 Jan 9. PMID 9422718
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    NM_128597.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within signal peptide processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast thylakoid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    thylakoid processing peptide
    NP_180603.2
    • thylakoid processing peptide (TPP); CONTAINS InterPro DOMAIN/s: Peptidase S24/S26A/S26B/S26C, beta-ribbon domain (InterPro:IPR011056), Peptidase S24/S26A/S26B/S26C (InterPro:IPR015927), Peptidase S26A, signal peptidase I, conserved site (InterPro:IPR019758), Peptidase S26, conserved region (InterPro:IPR019533), Peptidase S26A, signal peptidase I (InterPro:IPR000223), Peptidase S26A, signal peptidase I, serine active site (InterPro:IPR019756); BEST Arabidopsis thaliana protein match is: Peptidase S24/S26A/S26B/S26C family protein (TAIR:AT1G06870.1); Has 9797 Blast hits to 9593 proteins in 2427 species: Archae - 0; Bacteria - 7318; Metazoa - 215; Fungi - 115; Plants - 235; Viruses - 0; Other Eukaryotes - 1914 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12972682..12975542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128597.3 → NP_180603.2  thylakoid processing peptide [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180603.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04348, Q7DM64
      UniProtKB/TrEMBL
      A0A178VYT7, A0A5S9X2R9, A0A654F2L8
      Conserved Domains (1) summary
      pfam10502
      Location:157 → 317
      Peptidase_S26; Signal peptidase, peptidase S26
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04348.2

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