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    Excinuclease ABC, C subunit, N-terminal [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817585, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Excinuclease ABC, C subunit, N-terminal
    Primary source
    TAIR:AT2G30350
    Locus tag
    AT2G30350
    See related
    Araport:AT2G30350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T9D9.16; T9D9_16
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (12934149..12935784, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene GCN5L1 family protein Neighboring gene LOB domain-containing protein 13 Neighboring gene ncRNA Neighboring gene SOS3-interacting protein 4 Neighboring gene allergen-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism. Verma P, et al. Nucleic Acids Res, 2022 May 6. PMID 35412622, Free PMC Article
    2. HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana. Cho SK, et al. FEBS Lett, 2017 May. PMID 28321834
    3. Arabidopsis MAS2, an Essential Gene That Encodes a Homolog of Animal NF-κ B Activating Protein, Is Involved in 45S Ribosomal DNA Silencing. Sánchez-García AB, et al. Plant Cell, 2015 Jul. PMID 26139346, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism.
      Title: Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism.
    2. Results show the involvement of a novel gene, HYL1-interacting GIY-YIG-like endonuclease (HIGLE). The encoded protein has a GIY-YIG domain that is generally found within a class of homing endonucleases. HIGLE directly interacts with HYL1 and SE. Unlike the functions of other GIY-YIG endonucleases, the catalytic core of HIGLE has both DNase and RNase activities.[HIGLE]
      Title: HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128588.5
    NM_179811.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 5'-flap endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA endonuclease activity, producing 3'-phosphomonoesters IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables crossover junction DNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pre-miRNA 3'-end processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    part_of microprocessor complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Excinuclease ABC, C subunit, N-terminal
    NP_180594.2
    • Excinuclease ABC, C subunit, N-terminal; FUNCTIONS IN: nuclease activity; INVOLVED IN: DNA repair; LOCATED IN: intracellular; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Excinuclease ABC, C subunit, N-terminal (InterPro:IPR000305); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_850142.2
    • Excinuclease ABC, C subunit, N-terminal; Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12934149..12935784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128588.5 → NP_180594.2  Excinuclease ABC, C subunit, N-terminal [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180594.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUD7, A0A654EYX9, Q682H4
      Conserved Domains (1) summary
      cd10455
      Location:27 → 101
      GIY-YIG_SLX1; Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its eukaryotic homologs

    2. NM_179811.3 → NP_850142.2  Excinuclease ABC, C subunit, N-terminal [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850142.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IMS7
      Conserved Domains (1) summary
      cl15257
      Location:58 → 67
      GIY-YIG_SF; GIY-YIG nuclease domain superfamily
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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