U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FRO3 ferric reduction oxidase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838910, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FRO3
    Official Full Name
    ferric reduction oxidase 3
    Primary source
    TAIR:AT1G23020
    Locus tag
    AT1G23020
    See related
    Araport:AT1G23020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATFRO3; F19G10.4; F19G10_4; ferric reduction oxidase 3; FERRIC REDUCTION OXIDASE 3
    Summary
    Encodes a ferric chelate reductase whose transcription is regulated by FIT1. Expressed in the root, shoot, flower and cotyledon.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FRO3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (8149868..8153796, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene Cupredoxin superfamily protein Neighboring gene miscRNA Neighboring gene ARM repeat superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular and biochemical characterization of the Fe(III) chelate reductase gene family in Arabidopsis thaliana. Wu H, et al. Plant Cell Physiol, 2005 Sep. PMID 16006655
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help
    NM_001198138.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ferric-chelate reductase (NADH) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ferric-chelate reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ferric reduction oxidase 3
    NP_001185067.1
    • ferric reduction oxidase 3 (FRO3); FUNCTIONS IN: ferric-chelate reductase activity; INVOLVED IN: oxidation reduction; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Ferric reductase, NAD binding (InterPro:IPR013121), FAD-binding 8 (InterPro:IPR013112), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferric reductase-like transmembrane component, N-terminal (InterPro:IPR013130); BEST Arabidopsis thaliana protein match is: ferric reduction oxidase 1 (TAIR:AT1G01590.1).
    NP_001319065.1
    • ferric reduction oxidase 3 (FRO3); FUNCTIONS IN: ferric-chelate reductase activity; INVOLVED IN: oxidation reduction; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Ferric reductase, NAD binding (InterPro:IPR013121), FAD-binding 8 (InterPro:IPR013112), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferric reductase-like transmembrane component, N-terminal (InterPro:IPR013130); BEST Arabidopsis thaliana protein match is: ferric reduction oxidase 1 (TAIR:AT1G01590.1); Has 2651 Blast hits to 2646 proteins in 370 species: Archae - 2; Bacteria - 274; Metazoa - 566; Fungi - 1157; Plants - 480; Viruses - 0; Other Eukaryotes - 172 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8149868..8153796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332575.1 → NP_001319065.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9VMG3

    2. NM_001332576.1 → NP_001322197.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WM54

    3. NM_102150.4 → NP_173715.2  ferric reduction oxidase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173715.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9VMG3
      Conserved Domains (4) summary
      cd06186
      Location:352 → 535
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      PLN02292
      Location:27 → 716
      PLN02292; ferric-chelate reductase
      pfam01794
      Location:202 → 316
      Ferric_reduct; Ferric reductase like transmembrane component
      pfam08030
      Location:454 → 699
      NAD_binding_6; Ferric reductase NAD binding domain

    4. NM_001332577.1 → NP_001322198.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WM54

    5. NM_001332579.1 → NP_001322199.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WII5, A0A1P8ATB2

    6. NM_001332578.1 → NP_001322200.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WIK7, A0A1P8ATD5

    7. NM_001198138.1 → NP_001185067.1  ferric reduction oxidase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185067.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4K6, F4I4K7, O23122
      UniProtKB/TrEMBL
      A0A5S9VMG3
      Conserved Domains (4) summary
      cd06186
      Location:353 → 536
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      PLN02292
      Location:27 → 717
      PLN02292; ferric-chelate reductase
      pfam01794
      Location:203 → 317
      Ferric_reduct; Ferric reductase like transmembrane component
      pfam08030
      Location:455 → 700
      NAD_binding_6; Ferric reductase NAD binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4I4K7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.