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    PAI3 phosphoribosylanthranilate isomerase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839817, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAI3
    Official Full Name
    phosphoribosylanthranilate isomerase 3
    Primary source
    TAIR:AT1G29410
    Locus tag
    AT1G29410
    See related
    Araport:AT1G29410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15D2.31; F15D2_31; PHOSPHORIBOSYLANTHRANILATE ISOMERASE; phosphoribosylanthranilate isomerase 3
    Summary
    Encodes phosphoribosylanthranilate isomerase which catalyzes the third step in tryptophan biosynthesis.
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    Genomic context

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    See PAI3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (10297750..10300073, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene COLD REGULATED 314 INNER MEMBRANE 1 Neighboring gene MEI2-like protein 5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential expression of triplicate phosphoribosylanthranilate isomerase isogenes in the tryptophan biosynthetic pathway of Arabidopsis thaliana (L.) Heynh. He Y, et al. Planta, 2001 Apr. PMID 11346937
    2. Arabidopsis phosphoribosylanthranilate isomerase: molecular genetic analysis of triplicate tryptophan pathway genes. Li J, et al. Plant Cell, 1995 Apr. PMID 7773017, Free PMC Article
    3. Immunological characterization and chloroplast localization of the tryptophan biosynthetic enzymes of the flowering plant Arabidopsis thaliana. Zhao J, et al. J Biol Chem, 1995 Mar 17. PMID 7890741
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001332853.1
    NM_001332854.1
    NM_001332855.1
    NM_001332856.1
    NM_102681.4
    NM_180623.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphoribosylanthranilate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoribosylanthranilate isomerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables phosphoribosylanthranilate isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within multicellular organism development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in tryptophan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tryptophan biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phosphoribosylanthranilate isomerase 3
    NP_174234.3
    • phosphoribosylanthranilate isomerase 3 (PAI3); CONTAINS InterPro DOMAIN/s: N-(5'phosphoribosyl)anthranilate isomerase (PRAI) (InterPro:IPR001240), Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060); BEST Arabidopsis thaliana protein match is: phosphoribosylanthranilate isomerase 1 (TAIR:AT1G07780.4); Has 4015 Blast hits to 4015 proteins in 1696 species: Archae - 42; Bacteria - 3051; Metazoa - 2; Fungi - 223; Plants - 75; Viruses - 0; Other Eukaryotes - 622 (source: NCBI BLink).
    NP_850954.1
    • phosphoribosylanthranilate isomerase 3 (PAI3); CONTAINS InterPro DOMAIN/s: N-(5'phosphoribosyl)anthranilate isomerase (PRAI) (InterPro:IPR001240), Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060); BEST Arabidopsis thaliana protein match is: phosphoribosylanthranilate isomerase 1 (TAIR:AT1G07780.4); Has 3979 Blast hits to 3979 proteins in 1677 species: Archae - 42; Bacteria - 3011; Metazoa - 2; Fungi - 223; Plants - 75; Viruses - 0; Other Eukaryotes - 626 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10297750..10300073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332852.1 → NP_001322251.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ATF0
      Conserved Domains (1) summary
      PLN02363
      Location:4 → 223
      PLN02363; phosphoribosylanthranilate isomerase

    2. NM_180623.2 → NP_850954.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850954.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LPI9
      Conserved Domains (1) summary
      PLN02363
      Location:19 → 207
      PLN02363; phosphoribosylanthranilate isomerase

    3. NM_001332853.1 → NP_001322254.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42528, Q8LPI9, Q8VY51
      Conserved Domains (1) summary
      PLN02363
      Location:19 → 244
      PLN02363; phosphoribosylanthranilate isomerase

    4. NM_102681.4 → NP_174234.3  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174234.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42528, Q8LPI9, Q8VY51
      Conserved Domains (1) summary
      PLN02363
      Location:19 → 244
      PLN02363; phosphoribosylanthranilate isomerase

    5. NM_001332854.1 → NP_001322255.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ATF0
      Conserved Domains (1) summary
      PLN02363
      Location:4 → 223
      PLN02363; phosphoribosylanthranilate isomerase

    6. NM_001332855.1 → NP_001322252.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LPI9
      Conserved Domains (1) summary
      PLN02363
      Location:19 → 207
      PLN02363; phosphoribosylanthranilate isomerase

    7. NM_001332856.1 → NP_001322253.1  phosphoribosylanthranilate isomerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ATF1
      Conserved Domains (1) summary
      PLN02363
      Location:4 → 186
      PLN02363; phosphoribosylanthranilate isomerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LPI9.1

    Gene LinkOut

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