thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: thiamine diphosphate-binding fold (THDP-binding) superfamily protein
Primary source: TAIR:AT1G21400
Locus tag: AT1G21400
See related: Araport:AT1G21400
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F24J8.4; F24J8_4
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 9

Sequence:: Chromosome: 1; NC_003070.9 (7493213..7496741)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_101992.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within branched-chain amino acid catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cellular response to sucrose starvation	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to absence of light	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to sucrose	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: thiamine diphosphate-binding fold (THDP-binding) superfamily protein

NP_173562.1

Thiamin diphosphate-binding fold (THDP-binding) superfamily protein; FUNCTIONS IN: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; INVOLVED IN: metabolic process; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: Dehydrogenase, E1 component (InterPro:IPR001017); BEST Arabidopsis thaliana protein match is: Thiamin diphosphate-binding fold (THDP-binding) superfamily protein (TAIR:AT5G09300.1); Has 9510 Blast hits to 9506 proteins in 1925 species: Archae - 124; Bacteria - 6142; Metazoa - 513; Fungi - 243; Plants - 187; Viruses - 0; Other Eukaryotes - 2301 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

7493213..7496741

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001332499.1 → NP_001320427.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178WKT4, A0A1P8AMS6
NM_001332500.1 → NP_001320431.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178WKT4, A0A1P8AMW2
NM_001332501.1 → NP_001320429.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178WKT4, A0A1P8AMS6
NM_001332502.1 → NP_001320428.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AMS1, A0A654EBP3
NM_001332503.1 → NP_001320430.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AMS4
NM_101992.5 → NP_173562.1 thiamine diphosphate-binding fold (THDP-binding) superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_173562.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LPL5, Q9ZT57

UniProtKB/TrEMBL

A0A654EBP3

Conserved Domains (1) summary

cd02000
Location:133 → 425

TPP_E1_PDC_ADC_BCADC; Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain ...