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    CYCD1;1 CYCLIN D1;1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843357, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYCD1;1
    Official Full Name
    CYCLIN D1;1
    Primary source
    TAIR:AT1G70210
    Locus tag
    AT1G70210
    See related
    Araport:AT1G70210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCYCD1;1; CYCLIN D1;1; F20P5.7; F20P5_7
    Summary
    Encodes a D-type cyclin that physically interacts with CDC2A. Its expression is upregulated early during germination.
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    Genomic context

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    See CYCD1;1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (26439556..26443007)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7/L12 domain-containing protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-processing, Lsm domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis. Simonini S, et al. Dev Cell, 2021 Jul 12. PMID 34192526, Free PMC Article
    2. TCP7 functions redundantly with several Class I TCPs and regulates endoreplication in Arabidopsis. Zhang G, et al. J Integr Plant Biol, 2019 Nov. PMID 30474211
    3. Cyclin D1 and p22ack1 play opposite roles in plant growth and development. Cho JW, et al. Biochem Biophys Res Commun, 2004 Nov 5. PMID 15464981
    4. WOX5 suppresses CYCLIN D activity to establish quiescence at the center of the root stem cell niche. Forzani C, et al. Curr Biol, 2014 Aug 18. PMID 25127220, Free PMC Article
    5. Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2-type cyclin-dependent kinase. Kono A, et al. Plant Physiol, 2003 Jul. PMID 12857813, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis.
      Title: The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis.
    2. CYCLIN D1;1 (CYCD1;1) affects endoreplication in Arabidopsis; it is regulated by TCP7 and plays important roles during leaf and hypocotyl development
      Title: TCP7 functions redundantly with several Class I TCPs and regulates endoreplication in Arabidopsis.
    3. WOX5 restrains cell division in the cells of the quiescent center, thereby establishing quiescence. In contrast, WOX5 and CYCD3;3/CYCD1;1 both promote cell proliferation in the nascent columella.
      Title: WOX5 suppresses CYCLIN D activity to establish quiescence at the center of the root stem cell niche.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105689.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CYCLIN D1;1
    NP_177178.1
    • CYCLIN D1;1 (CYCD1;1); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: G1 phase of mitotic cell cycle, regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin D (InterPro:IPR015451), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin D2;1 (TAIR:AT2G22490.1); Has 3455 Blast hits to 3453 proteins in 343 species: Archae - 0; Bacteria - 0; Metazoa - 1586; Fungi - 382; Plants - 1073; Viruses - 13; Other Eukaryotes - 401 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26439556..26443007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105689.4 → NP_177178.1  CYCLIN D1;1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177178.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04525, P42751, Q8W2K2
      UniProtKB/TrEMBL
      A0A178W7L5
      Conserved Domains (2) summary
      cd20543
      Location:81 → 179
      CYCLIN_AtCycD-like_rpt1; first cyclin box found in plant cyclin-delta family
      cd20544
      Location:184 → 276
      CYCLIN_AtCycD-like_rpt2; second cyclin box found in plant cyclin-delta family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42751.3

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