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    Tex21 testis expressed gene 21 [ Mus musculus (house mouse) ]

    Gene ID: 80384, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tex21provided by MGI
    Official Full Name
    testis expressed gene 21provided by MGI
    Primary source
    MGI:MGI:1931131
    See related
    Ensembl:ENSMUSG00000021056 AllianceGenome:MGI:1931131
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    tsec-2; 4931406F04Rik; 4931412D23Rik; 4931421K24Rik
    Summary
    Orthologous to human TEX21P (testis expressed 21, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 15.7) See more
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    Genomic context

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    See Tex21 in Genome Data Viewer
    Location:
    12 C3; 12 33.52 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76245460..76293532, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76198686..76246758, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene spectrin repeat containing, nuclear envelope 2 Neighboring gene microRNA 5101 Neighboring gene STARR-seq mESC enhancer starr_32508 Neighboring gene estrogen receptor 2 (beta) Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr12:77297652-77297952 Neighboring gene STARR-seq mESC enhancer starr_32511 Neighboring gene STARR-seq mESC enhancer starr_32513 Neighboring gene STARR-positive B cell enhancer ABC_E4029 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Neighboring gene predicted gene, 40444 Neighboring gene predicted gene, 40443

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of a leucine zipper motif-containing novel cDNA specifically expressed in adult mouse testis. Chen L, et al. DNA Seq, 1998. PMID 10520738
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC118241

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC80384
    Names
    testis expressed gene 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159532.1 → NP_001153004.1  uncharacterized protein LOC80384 isoform 2

      See identical proteins and their annotated locations for NP_001153004.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site at its 3'terminus which results in a distinct 3' UTR, compared to variant 1, and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC100432, CR520719
      Consensus CDS
      CCDS88353.1
      UniProtKB/TrEMBL
      Q497Q3, Q9D4K1
      Related
      ENSMUSP00000151515.2, ENSMUST00000218426.2
      Conserved Domains (1) summary
      COG1196
      Location:88 → 480
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. NM_019784.5 → NP_062758.3  uncharacterized protein LOC80384 isoform 1

      See identical proteins and their annotated locations for NP_062758.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
      Source sequence(s)
      AK016471, BC100432, BX638105
      Consensus CDS
      CCDS25989.1
      UniProtKB/TrEMBL
      Q9D4K1, Q9R0U9
      Related
      ENSMUSP00000021453.5, ENSMUST00000021453.6
      Conserved Domains (1) summary
      COG1196
      Location:88 → 480
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      76245460..76293532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516393.3 → XP_006516456.1  uncharacterized protein LOC80384 isoform X1

      UniProtKB/TrEMBL
      Q9D4K1
      Conserved Domains (2) summary
      COG1196
      Location:33 → 420
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR03185
      Location:13 → 136
      DNA_S_dndD; DNA sulfur modification protein DndD

    2. XM_006516394.2 → XP_006516457.1  uncharacterized protein LOC80384 isoform X2

      UniProtKB/TrEMBL
      Q9D4K1
      Conserved Domains (2) summary
      COG1196
      Location:87 → 454
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK03918
      Location:78 → 214
      PRK03918; DNA double-strand break repair ATPase Rad50
    Nucleotide Protein Strain
    Heading Accession and Version

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