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    Myadml2 myeloid-associated differentiation marker-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 68515, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Myadml2provided by MGI
    Official Full Name
    myeloid-associated differentiation marker-like 2provided by MGI
    Primary source
    MGI:MGI:1915765
    See related
    Ensembl:ENSMUSG00000025141 AllianceGenome:MGI:1915765
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110012N22Rik
    Summary
    Predicted to be located in cytoplasm. Orthologous to human MYADML2 (myeloid associated differentiation marker like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in heart adult (RPKM 23.9), mammary gland adult (RPKM 7.7) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Myadml2 in Genome Data Viewer
    Location:
    11 E2; 11 84.37 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120536857..120539188, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120646031..120648337, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7115 Neighboring gene v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) Neighboring gene predicted gene, 17586 Neighboring gene STARR-positive B cell enhancer mm9_chr11:120504984-120505285 Neighboring gene pyrroline-5-carboxylate reductase 1 Neighboring gene notum palmitoleoyl-protein carboxylesterase Neighboring gene STARR-seq mESC enhancer starr_31365 Neighboring gene ASPSCR1 tether for SLC2A4, UBX domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107698

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    myeloid-associated differentiation marker-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204820.1 → NP_001191749.1  myeloid-associated differentiation marker-like protein 2 isoform 2

      See identical proteins and their annotated locations for NP_001191749.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK003645, AL663030, BC091000
      Consensus CDS
      CCDS56828.1
      UniProtKB/Swiss-Prot
      Q08AU7
      Related
      ENSMUSP00000026134.3, ENSMUST00000026134.3
      Conserved Domains (1) summary
      pfam01284
      Location:17 → 115
      MARVEL; Membrane-associating domain

    2. NM_026751.1 → NP_081027.1  myeloid-associated differentiation marker-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_081027.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL663030, BC091000, BC109329, BY636421
      Consensus CDS
      CCDS88298.1
      UniProtKB/Swiss-Prot
      Q08AU7, Q5BKP1, Q9D1F1
      Related
      ENSMUSP00000158986.2, ENSMUST00000239158.2
      Conserved Domains (1) summary
      pfam01284
      Location:159 → 297
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      120536857..120539188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314729.3 → XP_017170218.1  myeloid-associated differentiation marker-like protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q08AU7, Q5BKP1, Q9D1F1
      Conserved Domains (1) summary
      pfam01284
      Location:159 → 297
      MARVEL; Membrane-associating domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08AU7.2 GenPept UniProtKB/Swiss-Prot:Q08AU7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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