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    PIP1B plasma membrane intrinsic protein 1B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819204, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP1B
    Official Full Name
    plasma membrane intrinsic protein 1B
    Primary source
    TAIR:AT2G45960
    Locus tag
    AT2G45960
    See related
    Araport:AT2G45960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATHH2; F4I18.6; NAMED PLASMA MEMBRANE INTRINSIC PROTEIN 1;2; PIP1;2; plasma membrane intrinsic protein 1B; TMP-A; TRANSMEMBRANE PROTEIN A
    Summary
    a member of the plasma membrane intrinsic protein subfamily PIP1. localizes to the plasma membrane and exhibits water transport activity in Xenopus oocyte. expressed ubiquitously and protein level decreases slightly during leaf development.
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    Genomic context

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    See PIP1B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (18910081..18911982)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene hypothetical protein (DUF295) Neighboring gene ncRNA Neighboring gene SKP1-like 20 Neighboring gene cytochrome P450, family 86, subfamily A, polypeptide 8 Neighboring gene mesoderm induction early response protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress. Aharon R, et al. Plant Cell, 2003 Feb. PMID 12566583, Free PMC Article
    2. T-DNA insertion in aquaporin gene AtPIP1;2 generates transcription profiles reminiscent of a low CO2 response. Boudichevskaia A, et al. Plant Cell Environ, 2015 Nov. PMID 25850563
    3. A PIP1 aquaporin contributes to hydrostatic pressure-induced water transport in both the root and rosette of Arabidopsis. Postaire O, et al. Plant Physiol, 2010 Mar. PMID 20034965, Free PMC Article
    4. The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO₂ transport facilitator. Heckwolf M, et al. Plant J, 2011 Sep. PMID 21564354
    5. The Arabidopsis aquaporin PIP1;2 rules cellular CO(2) uptake. Uehlein N, et al. Plant Cell Environ, 2012 Jun. PMID 22150826

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results identified 2 members of the receptor-like kinase (RLK) family (RKL1 (At1g48480) and Feronia (At3g51550)) differentially modulate PIP1;2 and PIP2;1 activity through distinct molecular mechanisms.
      Title: Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics.
    2. The AtPIP1;2 function in plant physiology is to facilitate CO2 diffusion.
      Title: T-DNA insertion in aquaporin gene AtPIP1;2 generates transcription profiles reminiscent of a low CO2 response.
    3. The AtPIP1;2 gene product limits CO diffusion and photosynthesis in leaves.
      Title: The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO₂ transport facilitator.
    4. Cellular CO(2) transport was not limited by unstirred layer effects but was dependent on the expression of the aquaporin AtPIP1;2.
      Title: The Arabidopsis aquaporin PIP1;2 rules cellular CO(2) uptake.
    5. The expression of both AtPIP1;2 and AtPIP2;1 oscillated with the circadian rhythm under low light conditions in wild-type seedlings, but not in the elf3 mutant.
      Title: The circadian clock modulates water dynamics and aquaporin expression in Arabidopsis roots.
    6. AtPIP1;2 significantly contributes to the hydraulic conductivity of both roots and rosette.
      Title: A PIP1 aquaporin contributes to hydrostatic pressure-induced water transport in both the root and rosette of Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084597.1
    NM_001084598.1
    NM_130159.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables water channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbon dioxide transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within water transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plasma membrane intrinsic protein 1B
    NP_001078066.1
    • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10376 Blast hits to 10338 proteins in 2169 species: Archae - 101; Bacteria - 4994; Metazoa - 1330; Fungi - 442; Plants - 2464; Viruses - 0; Other Eukaryotes - 1045 (source: NCBI BLink).
    NP_001078067.1
    • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10384 Blast hits to 10346 proteins in 2170 species: Archae - 101; Bacteria - 5000; Metazoa - 1330; Fungi - 442; Plants - 2465; Viruses - 0; Other Eukaryotes - 1046 (source: NCBI BLink).
    NP_182120.1
    • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: anchored to plasma membrane, plasma membrane, chloroplast, vacuole, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10777 Blast hits to 10745 proteins in 2215 species: Archae - 97; Bacteria - 5153; Metazoa - 1470; Fungi - 452; Plants - 2515; Viruses - 2; Other Eukaryotes - 1088 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18910081..18911982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130159.4 → NP_182120.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182120.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q06611, Q8L5V4
      UniProtKB/TrEMBL
      A0A178VYL1, A0A384KNK4, A0A7G2EE24, D9IX99
      Conserved Domains (1) summary
      pfam00230
      Location:44 → 273
      MIP; Major intrinsic protein

    2. NM_001084597.1 → NP_001078066.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EE24, B9DFR9
      Conserved Domains (1) summary
      pfam00230
      Location:44 → 255
      MIP; Major intrinsic protein

    3. NM_001084598.1 → NP_001078067.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078067.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EE24, A8MRW1
      Conserved Domains (1) summary
      pfam00230
      Location:44 → 261
      MIP; Major intrinsic protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06611.1

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