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    adenylate cyclase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815664, updated on 18-Sep-2024

    Summary

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    Official Full Name
    adenylate cyclase
    Primary source
    TAIR:AT2G11890
    Locus tag
    AT2G11890
    See related
    Araport:AT2G11890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTTM3; Triphosphate Tunnel Metalloenzyme 3; TTM3
    Summary
    adenylate cyclase
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (4802783..4804375)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants. Lorenzo-Orts L, et al. Nat Plants, 2019 Feb. PMID 30737513
    2. Crystal structure and biochemical analyses reveal that the Arabidopsis triphosphate tunnel metalloenzyme AtTTM3 is a tripolyphosphatase involved in root development. Moeder W, et al. Plant J, 2013 Nov. PMID 24004165
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TTM3 coordinates CDC26 translation by recruiting the transcript into polysomes.CDC26 and TTM3 are translated from a single transcript conserved across the plant lineage.
      Title: Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants.
    2. Crystal structure reveals that Arabidopsis metalloenzyme TTM3 is a tripolyphosphatase involved in root development
      Title: Crystal structure and biochemical analyses reveal that the Arabidopsis triphosphate tunnel metalloenzyme AtTTM3 is a tripolyphosphatase involved in root development.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Miscellaneous features

    • Loc: 4802793-4802990 AT2G11890.uORF1
    NM_001036270.1
    NM_126867.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inorganic triphosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate cyclase
    NP_001031347.1
    • adenylate cyclases; FUNCTIONS IN: adenylate cyclase activity; INVOLVED IN: cAMP biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenylate cyclase (InterPro:IPR008172); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_565353.1
    • adenylate cyclases; FUNCTIONS IN: adenylate cyclase activity; INVOLVED IN: cAMP biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenylate cyclase (InterPro:IPR008172); Has 74 Blast hits to 74 proteins in 26 species: Archae - 0; Bacteria - 18; Metazoa - 0; Fungi - 0; Plants - 51; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      4802783..4804375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036270.1 → NP_001031347.1  adenylate cyclase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031347.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E976
      Conserved Domains (1) summary
      cd07374
      Location:2 → 127
      CYTH-like_Pase; CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases

    2. NM_126867.2 → NP_565353.1  adenylate cyclase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565353.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG04, Q9SIY3
      UniProtKB/TrEMBL
      A0A178VXF3, A0A5S9WXZ5
      Conserved Domains (1) summary
      cd07374
      Location:2 → 164
      CYTH-like_Pase; CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SIY3.1

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