ARF1A1C Ras-related small GTP-binding family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ARF1A1C
Official Full Name: Ras-related small GTP-binding family protein
Primary source: TAIR:AT2G47170
Locus tag: AT2G47170
See related: Araport:AT2G47170
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ADP-RIBOSYLATION FACTOR; BEX1; bfa-visualized exocytic trafficking defective 1; T8I13.1
Summary: Gene encoding ADP-ribosylation factor and similar to other ARFs and ARF-like proteins. Members of this family are known to be essential for vesicle coating and uncoating and functions in GTP-binding. The gene is shown to play a role in cell division, cell expansion and cellulose production using antisense construct.
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Genomic context

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See ARF1A1C in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 7

Sequence:: Chromosome: 2; NC_003071.7 (19366596..19368840)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ARF1A1C is essential for recycling of PIN auxin transporters and for various auxin-dependent developmental processes.[BEX1][ARF1A1C]
Title: BEX1/ARF1A1C is required for BFA-sensitive recycling of PIN auxin transporters and auxin-mediated development in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001337250.1

Supported by ESTs:

NM_001337251.1

Supported by ESTs:

NM_130285.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTP binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables GTP binding	TAS Traceable Author Statement more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables phospholipase activator activity	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of auxin metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to brefeldin A	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle-mediated transport to the plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi apparatus	ISM Inferred from Sequence Model more info
located_in Golgi-associated vesicle	IDA Inferred from Direct Assay more info
located_in cytosol	HDA more info	PubMed
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in early endosome	IDA Inferred from Direct Assay more info	PubMed
located_in trans-Golgi network	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Ras-related small GTP-binding family protein

NP_182239.1

ARF1A1C; FUNCTIONS IN: phospholipase activator activity, GTP binding; INVOLVED IN: N-terminal protein myristoylation; LOCATED IN: Golgi-associated vesicle; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ADP-ribosylation factor (InterPro:IPR006688), Small GTP-binding protein (InterPro:IPR005225), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: ADP-ribosylation factor A1F (TAIR:AT1G10630.1); Has 15041 Blast hits to 15022 proteins in 509 species: Archae - 14; Bacteria - 51; Metazoa - 7725; Fungi - 1942; Plants - 2032; Viruses - 3; Other Eukaryotes - 3274 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

19366596..19368840

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_130285.3 → NP_182239.1 Ras-related small GTP-binding family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_182239.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P36397, Q7G9L3

UniProtKB/TrEMBL

A0A178VXE5, A0A5S9X7P9, A0A654G139

Conserved Domains (1) summary

PLN00223
Location:1 → 181

PLN00223; ADP-ribosylation factor; Provisional
NM_001337250.1 → NP_001324310.1 Ras-related small GTP-binding family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

P36397, Q7G9L3

UniProtKB/TrEMBL

A0A178VXE5, A0A5S9X7P9, A0A654G139

Conserved Domains (1) summary

PLN00223
Location:1 → 181

PLN00223; ADP-ribosylation factor; Provisional
NM_001337251.1 → NP_001324311.1 Ras-related small GTP-binding family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

P36397, Q7G9L3

UniProtKB/TrEMBL

A0A178VXE5, A0A5S9X7P9, A0A654G139

Conserved Domains (1) summary

PLN00223
Location:1 → 181

PLN00223; ADP-ribosylation factor; Provisional