U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SULTR1;2 sulfate transporter 1;2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844135, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SULTR1;2
    Official Full Name
    sulfate transporter 1;2
    Primary source
    TAIR:AT1G78000
    Locus tag
    AT1G78000
    See related
    Araport:AT1G78000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F28K19.22; F28K19_22; SEL1; SELENATE RESISTANT 1; SULFATE TRANSPORTER; sulfate transporter 1;2
    Summary
    Encodes a sulfate transporter that can restore sulfate uptake capacity of a yeast mutant lacking sulfate transporter genes.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SULTR1;2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (29327515..29333220)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene AGAMOUS-like 66 Neighboring gene STAS domain / Sulfate transporter family Neighboring gene ncRNA Neighboring gene tRNA modification GTPase Neighboring gene senescence-associated family protein, putative (DUF581)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Plants prioritize phytochelatin synthesis during cadmium exposure even under reduced sulfate uptake caused by the disruption of SULTR1;2. Yamaguchi C, et al. Plant Signal Behav, 2017 May 4. PMID 28486013, Free PMC Article
    2. Mechanisms of the selenium tolerance of the Arabidopsis thaliana knockout mutant of sulfate transporter SULTR1;2. Ohno M, et al. Biosci Biotechnol Biochem, 2012. PMID 22738972
    3. Identification and regulation of plasma membrane sulfate transporters in Chlamydomonas. Pootakham W, et al. Plant Physiol, 2010 Aug. PMID 20498339, Free PMC Article
    4. Characterization of a selenate-resistant Arabidopsis mutant. Root growth as a potential target for selenate toxicity. El Kassis E, et al. Plant Physiol, 2007 Mar. PMID 17208959, Free PMC Article
    5. The role of the STAS domain in the function and biogenesis of a sulfate transporter as probed by random mutagenesis. Shibagaki N, et al. J Biol Chem, 2006 Aug 11. PMID 16754669

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Plants prioritize phytochelatin synthesis during cadmium exposure even under reduced sulfate uptake caused by the disruption of SULTR1;2
      Title: Plants prioritize phytochelatin synthesis during cadmium exposure even under reduced sulfate uptake caused by the disruption of SULTR1;2.
    2. The sultr1;2 mutation confers Se tolerance on Arabidopsis by decreasing symplastic Se and maintaining antioxidant enzyme activities.
      Title: Mechanisms of the selenium tolerance of the Arabidopsis thaliana knockout mutant of sulfate transporter SULTR1;2.
    3. analysis of a regulatory model in which interactions between SULTR1;2 and OASTL coordinate internalization of SO(4)(2-) with the energetic/metabolic state of plant root cells
      Title: Binding of cysteine synthase to the STAS domain of sulfate transporter and its regulatory consequences.
    4. The SULTR1;1 and SULTR1;2 genes display unequal functional redundancy, which leaves open for SULTR1;1 the possibility of displaying an additional function besides its role in sulphate membrane transport
      Title: Unequal functional redundancy between the two Arabidopsis thaliana high-affinity sulphate transporters SULTR1;1 and SULTR1;2.
    5. expression of SULTR1.1 is locally regulated in response to sulfate starvation. In contrast, accumulation of SULTR1.2 transcripts appeared to be mainly related to metabolic demand and is controlled by photoperiod
      Title: Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis.
    6. SULTR1;1 and SULTR1;2 are two essential components of the sulfate uptake system in roots and are regulated at posttranscriptional levels together with the previously reported transcriptional control.
      Title: Posttranscriptional regulation of high-affinity sulfate transporters in Arabidopsis by sulfur nutrition.
    7. The transporter SULTR1;2 has a central and specific role in selenate sensitivity
      Title: Characterization of a selenate-resistant Arabidopsis mutant. Root growth as a potential target for selenate toxicity.
    8. STAS domain is involved in protein-protein interactions that could control sulfate transport
      Title: Structural and functional analysis of the C-terminal STAS (sulfate transporter and anti-sigma antagonist) domain of the Arabidopsis thaliana sulfate transporter SULTR1.2.
    9. the STAS domain is critical for both the activity and biosynthesis/stability of the transporter, and the STAS sub-domains correlate with these specific functions
      Title: The role of the STAS domain in the function and biogenesis of a sulfate transporter as probed by random mutagenesis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001334812.1
    NM_001334813.1
    NM_106449.3
    NM_179568.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables secondary active sulfate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sulfate transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables sulfate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to sulfate starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within selenate transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfate transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    sulfate transporter 1;2
    NP_565166.1
    • sulfate transporter 1;2 (SULTR1;2); CONTAINS InterPro DOMAIN/s: Sulphate transporter (InterPro:IPR011547), Sulphate transporter/antisigma-factor antagonist STAS (InterPro:IPR002645), Sulphate anion transporter, conserved site (InterPro:IPR018045), Sulphate anion transporter (InterPro:IPR001902); BEST Arabidopsis thaliana protein match is: sulfate transporter 1;3 (TAIR:AT1G22150.1); Has 10127 Blast hits to 10032 proteins in 1879 species: Archae - 35; Bacteria - 6193; Metazoa - 1167; Fungi - 451; Plants - 560; Viruses - 0; Other Eukaryotes - 1721 (source: NCBI BLink).
    NP_849899.1
    • sulfate transporter 1;2 (SULTR1;2); CONTAINS InterPro DOMAIN/s: Sulphate transporter (InterPro:IPR011547), Sulphate transporter/antisigma-factor antagonist STAS (InterPro:IPR002645), Sulphate anion transporter, conserved site (InterPro:IPR018045), Sulphate anion transporter (InterPro:IPR001902); BEST Arabidopsis thaliana protein match is: sulfate transporter 1;3 (TAIR:AT1G22150.1); Has 10127 Blast hits to 10032 proteins in 1879 species: Archae - 35; Bacteria - 6193; Metazoa - 1167; Fungi - 451; Plants - 560; Viruses - 0; Other Eukaryotes - 1721 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29327515..29333220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334809.1 → NP_001321366.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTN0, Q9MAX3, Q9SH00
      UniProtKB/TrEMBL
      A0A5S9WVB8, A0A654EPY0
      Conserved Domains (1) summary
      TIGR00815
      Location:77 → 641
      sulP; high affinity sulphate transporter 1

    2. NM_001334810.1 → NP_001321365.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQM4, A0A5S9WVB8

    3. NM_001334811.1 → NP_001321364.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQP6, A0A5S9WVB8

    4. NM_106449.3 → NP_565166.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565166.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTN0, Q9MAX3, Q9SH00
      UniProtKB/TrEMBL
      A0A5S9WVB8, A0A654EPY0
      Conserved Domains (1) summary
      TIGR00815
      Location:77 → 641
      sulP; high affinity sulphate transporter 1

    5. NM_179568.2 → NP_849899.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849899.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTN0, Q9MAX3, Q9SH00
      UniProtKB/TrEMBL
      A0A5S9WVB8, A0A654EPY0
      Conserved Domains (1) summary
      TIGR00815
      Location:77 → 641
      sulP; high affinity sulphate transporter 1

    6. NM_001334812.1 → NP_001321363.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQR2

    7. NM_001334813.1 → NP_001321362.1  sulfate transporter 1;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQN0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MAX3.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.