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    basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 6240759, updated on 18-Sep-2024

    Summary

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    Official Full Name
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    Primary source
    TAIR:AT1G29950
    Locus tag
    AT1G29950
    See related
    Araport:AT1G29950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T1P2.2
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (10491698..10494598)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene chlorophyll A/B binding protein 1 Neighboring gene nuclear RNA polymerase A2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peptidase S24/S26A/S26B/S26C family protein Neighboring gene AGAMOUS-like 64

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantification of Xylem-Specific Thermospermine-Dependent Translation of SACL Transcripts with Dual Luciferase Reporter System. Solé-Gil A, et al. Methods Mol Biol, 2024. PMID 37897601
    2. The SAC51 Family Plays a Central Role in Thermospermine Responses in Arabidopsis. Cai Q, et al. Plant Cell Physiol, 2016 Aug. PMID 27388339
    3. The Arabidopsis basic/helix-loop-helix transcription factor family. Toledo-Ortiz G, et al. Plant Cell, 2003 Aug. PMID 12897250, Free PMC Article
    4. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534
    5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Miscellaneous features

    • Loc: 10492498-10492575 AT1G29950.uORF1
    • Loc: 10492790-10492897 AT1G29950.uORF2-1
    • Loc: 10493066-10493104 AT1G29950.uORF2-2
    NM_102735.3
    NM_202208.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in xylem development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    NP_564342.1
    • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: transcription regulator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: sequence-specific DNA binding transcription factors;transcription regulators (TAIR:AT5G50010.1); Has 770 Blast hits to 729 proteins in 71 species: Archae - 0; Bacteria - 2; Metazoa - 29; Fungi - 28; Plants - 411; Viruses - 2; Other Eukaryotes - 298 (source: NCBI BLink).
    NP_973937.1
    • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: transcription regulator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: sequence-specific DNA binding transcription factors;transcription regulators (TAIR:AT5G50010.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10491698..10494598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102735.3 → NP_564342.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564342.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q681I6, Q9ASX9, Q9FXG5
      UniProtKB/TrEMBL
      A0A178WGL6, A0A5S9WCL6, A0A7G2DWY5, C0Z288
      Conserved Domains (1) summary
      cd18917
      Location:208 → 243
      bHLH_AtSAC51_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana suppressor of acaulis 51 (SAC51) and similar proteins

    2. NM_202208.1 → NP_973937.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973937.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q681I6, Q9ASX9, Q9FXG5
      UniProtKB/TrEMBL
      A0A178WGL6, A0A5S9WCL6, A0A7G2DWY5, C0Z288
      Conserved Domains (1) summary
      cd18917
      Location:208 → 243
      bHLH_AtSAC51_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana suppressor of acaulis 51 (SAC51) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ASX9.1

    Gene LinkOut

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    Research Materials