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    SCL30 SC35-like splicing factor 30 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824712, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SCL30
    Official Full Name
    SC35-like splicing factor 30
    Primary source
    TAIR:AT3G55460
    Locus tag
    AT3G55460
    See related
    Araport:AT3G55460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    At-SCL30; SC35-like splicing factor 30
    Summary
    encodes an SC35-like splicing factor that is localized to nuclear specks. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
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    Genomic context

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    See SCL30 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (20560802..20563885)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene triosephosphate isomerase Neighboring gene PBS1-like 1 Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene protein affected trafficking 2 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamic nucleocytoplasmic shuttling of an Arabidopsis SR splicing factor: role of the RNA-binding domains. Rausin G, et al. Plant Physiol, 2010 May. PMID 20237019, Free PMC Article
    2. Interactions of Arabidopsis RS domain containing cyclophilins with SR proteins and U1 and U11 small nuclear ribonucleoprotein-specific proteins suggest their involvement in pre-mRNA Splicing. Lorkovic ZJ, et al. J Biol Chem, 2004 Aug 6. PMID 15166240
    3. Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei. Lorković ZJ, et al. Exp Cell Res, 2008 Oct 15. PMID 18674533
    4. Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors. Lopato S, et al. J Biol Chem, 2002 Oct 18. PMID 12176998
    5. AtCyp59 is a multidomain cyclophilin from Arabidopsis thaliana that interacts with SR proteins and the C-terminal domain of the RNA polymerase II. Gullerova M, et al. RNA, 2006 Apr. PMID 16497658, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_115404.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SC35-like splicing factor 30
    NP_567021.1
    • SC35-like splicing factor 30 (SCL30); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: response to oxidative stress, nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: nuclear speck; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 999798 Blast hits to 999477 proteins in 36048 species: Archae - 21842; Bacteria - 604317; Metazoa - 201442; Fungi - 24075; Plants - 55248; Viruses - 69771; Other Eukaryotes - 23103 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20560802..20563885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115404.6 → NP_567021.1  SC35-like splicing factor 30 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567021.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L3X8, Q9FYA9, Q9M2T3
      UniProtKB/TrEMBL
      A0A178VM76, A0A5S9XL17
      Conserved Domains (1) summary
      smart00360
      Location:49 → 120
      RRM; RNA recognition motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L3X8.1

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