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    Ptcra pre T cell antigen receptor alpha [ Mus musculus (house mouse) ]

    Gene ID: 19208, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptcraprovided by MGI
    Official Full Name
    pre T cell antigen receptor alphaprovided by MGI
    Primary source
    MGI:MGI:104857
    See related
    Ensembl:ENSMUSG00000036858 AllianceGenome:MGI:104857
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    pTa; gp33; pT[a]; pTalpha; pT-alpha; pT-alpha-TCR
    Summary
    Acts upstream of or within negative regulation of thymocyte apoptotic process. Predicted to be located in plasma membrane. Is expressed in thymus and thymus primordium. Orthologous to human PTCRA (pre T cell antigen receptor alpha). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward thymus adult (RPKM 45.7) See more
    Orthologs
    NEW
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    Genomic context

    See Ptcra in Genome Data Viewer
    Location:
    17 C; 17 22.9 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (47066589..47074659, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46755663..46763712, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene glycine N-methyltransferase Neighboring gene canopy FGF signaling regulator 3 Neighboring gene STARR-positive B cell enhancer ABC_E2490 Neighboring gene STARR-positive B cell enhancer ABC_E3204 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:46900557-46900758 Neighboring gene peroxisomal biogenesis factor 39 Neighboring gene ribosomal protein L7-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E7539

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (5)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    pre T-cell antigen receptor alpha

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011195.3NP_035325.2  pre T-cell antigen receptor alpha precursor

      Status: VALIDATED

      Source sequence(s)
      CT030702
      Consensus CDS
      CCDS28840.1
      UniProtKB/Swiss-Prot
      P0C6B2
      UniProtKB/TrEMBL
      A0A0R4J0F4
      Related
      ENSMUSP00000035683.10, ENSMUST00000041012.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      47066589..47074659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)