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    Cramp1 cramped chromatin regulator homolog 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287127, updated on 3-Dec-2024

    Summary

    Official Symbol
    Cramp1provided by RGD
    Official Full Name
    cramped chromatin regulator homolog 1provided by RGD
    Primary source
    RGD:1311948
    See related
    EnsemblRapid:ENSRNOG00000024635 AllianceGenome:RGD:1311948
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cramp1l
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in pattern specification process. Predicted to be active in nucleus. Orthologous to human CRAMP1 (cramped chromatin regulator homolog 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 46.7), Spleen (RPKM 41.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cramp1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (14488292..14536844, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13983781..14032409, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14324799..14373413, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 8 interacting protein 3 Neighboring gene uncharacterized LOC134480762 Neighboring gene Jupiter microtubule associated homolog 2 Neighboring gene uncharacterized LOC134480761 Neighboring gene intraflagellar transport 140 Neighboring gene transmembrane protein 204

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in pattern specification process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein cramped-like
    Names
    Crm, cramped-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427759.1NP_001414688.1  protein cramped-like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6ADH2
      Related
      ENSRNOP00000092155.2, ENSRNOT00000110817.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      14488292..14536844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268565.1XP_063124635.1  protein cramped-like isoform X3

      UniProtKB/TrEMBL
      A0A8I6ADH2
    2. XM_063268566.1XP_063124636.1  protein cramped-like isoform X4

      UniProtKB/TrEMBL
      A0A8I6ADH2
    3. XM_017597599.3XP_017453088.1  protein cramped-like isoform X1

      UniProtKB/TrEMBL
      A0A8I6ADH2
    4. XM_017597600.3XP_017453089.1  protein cramped-like isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADH2
      Related
      ENSRNOP00000022050.6, ENSRNOT00000022050.8