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    Naa16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 686240, updated on 3-Dec-2024

    Summary

    Official Symbol
    Naa16provided by RGD
    Official Full Name
    N(alpha)-acetyltransferase 16, NatA auxiliary subunitprovided by RGD
    Primary source
    RGD:1584324
    See related
    EnsemblRapid:ENSRNOG00000045863 AllianceGenome:RGD:1584324
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acetyltransferase activator activity and ribosome binding activity. Predicted to be involved in N-terminal protein amino acid acetylation; negative regulation of apoptotic process; and protein stabilization. Predicted to be located in cytosol. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Orthologous to human NAA16 (N-alpha-acetyltransferase 16, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 109.4), Spleen (RPKM 89.5) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Naa16 in Genome Data Viewer
    Location:
    15q12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (61120704..61179979, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (54711620..54770915, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (61597054..61655665, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene regulator of cell cycle Neighboring gene glutamate-ammonia ligase, pseudogene 1 Neighboring gene U2 spliceosomal RNA Neighboring gene mitochondrial translation release factor 1 Neighboring gene kelch repeat and BTB domain containing 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acetyltransferase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NatA complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 16, NatA auxiliary subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399534.1NP_001386463.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A0A8I6AQN9, A6HTY9, M0RC73
      Related
      ENSRNOP00000067183.3, ENSRNOT00000071805.4
      Conserved Domains (4) summary
      COG4783
      Location:103251
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      61120704..61179979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274645.1XP_063130715.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1

    2. XM_039094047.2XP_038949975.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1

      Conserved Domains (4) summary
      COG4783
      Location:103251
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam12569
      Location:187513
      NARP1; NMDA receptor-regulated protein 1
    3. XM_063274646.1XP_063130716.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X2

    RNA

    1. XR_010057850.1 RNA Sequence

    2. XR_010057851.1 RNA Sequence

    3. XR_010057849.1 RNA Sequence

    4. XR_010057853.1 RNA Sequence

    5. XR_010057852.1 RNA Sequence