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    Tmem183a transmembrane protein 183A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289034, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem183aprovided by RGD
    Official Full Name
    transmembrane protein 183Aprovided by RGD
    Primary source
    RGD:1309892
    See related
    EnsemblRapid:ENSRNOG00000003594 AllianceGenome:RGD:1309892
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem183; RGD1309892
    Summary
    Predicted to be involved in regulation of protein stability. Predicted to be located in membrane. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to several human genes including TMEM183A (transmembrane protein 183A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 386.2), Liver (RPKM 277.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem183a in Genome Data Viewer
    Location:
    13q13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (48355664..48372437, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (45803641..45820409, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (51184647..51201401, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096189 Neighboring gene myogenin Neighboring gene PTPRF interacting protein alpha 4 Neighboring gene Mgat4 family, member E-like Neighboring gene uncharacterized LOC120096190 Neighboring gene cytochrome b5 reductase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of protein stability IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 183
    Names
    clone MNCb-2755

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013871.1NP_001013893.1  transmembrane protein 183

      See identical proteins and their annotated locations for NP_001013893.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079375
      UniProtKB/Swiss-Prot
      Q68FS7
      UniProtKB/TrEMBL
      A0A0G2JT36, A6ICB4
      Related
      ENSRNOP00000096186.1, ENSRNOT00000100649.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      48355664..48372437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006249850.5XP_006249912.1  transmembrane protein 183 isoform X2

      UniProtKB/TrEMBL
      A0A0G2JT36, A0A8L2Q253
      Related
      ENSRNOP00000005272.4, ENSRNOT00000005272.7
    2. XM_006249849.5XP_006249911.1  transmembrane protein 183 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JT36

    RNA

    1. XR_005492211.2 RNA Sequence

    2. XR_005492212.2 RNA Sequence