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    Vti1a Vesicle transport through interaction with t-SNAREs 1a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38085, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vti1aprovided by FlyBase
    Official Full Name
    Vesicle transport through interaction with t-SNAREs 1aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260862
    Locus tag
    Dmel_CG3279
    See related
    AllianceGenome:FB:FBgn0260862
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3279; Dmel\CG3279; Vti1; VTI1; vti1a; Vti1A
    Summary
    Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in Golgi vesicle transport; macroautophagy; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane and clathrin-coated vesicle. Predicted to be part of SNARE complex. Predicted to be active in Golgi apparatus; cytoplasmic vesicle membrane; and endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human VTI1A (vesicle transport through interaction with t-SNAREs 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Vti1a in Genome Data Viewer
    Location:
    61C8-61C8; 3-0.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (691486..692919, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (691486..692919, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene highroad Neighboring gene uncharacterized protein Neighboring gene RabX6 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44514

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables SNAP receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in macroautophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retrograde transport, endosome to Golgi ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vesicle fusion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vesicle fusion with Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vesicle fusion with Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in ER to Golgi transport vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SNARE complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in clathrin-coated vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    vesicle transport through interaction with t-SNAREs 1a
    Names
    CG3279-PA
    VTI1 ortholog
    Vti1a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      691486..692919 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138209.4NP_612053.1  vesicle transport through interaction with t-SNAREs 1a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612053.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0N6
      Related
      FBpp0072503
      Conserved Domains (2) summary
      cd15891
      Location:128189
      SNARE_Vti1a; SNARE motif of Vti1b-like
      pfam05008
      Location:1189
      V-SNARE; Vesicle transport v-SNARE protein N-terminus