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    CG15011 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38518, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15011provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035518
    Locus tag
    Dmel_CG15011
    See related
    AllianceGenome:FB:FBgn0035518
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg15011; Dmel\CG15011
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in larval muscle system and organism. Orthologous to human NFXL1 (nuclear transcription factor, X-box binding like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15011 in Genome Data Viewer
    Location:
    64A12-64A12; 3-10 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4255991..4259152, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4255991..4259152, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pavarotti Neighboring gene archipelago Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vacuolar H[+] ATPase M9.7 subunit a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Chlamydas S, et al. Nat Struct Mol Biol, 2016 Jun. PMID 27183194
    2. Drosophila Trf4-1 involves in mRNA and primary miRNA transcription. Liu Y, et al. Biochem Biophys Res Commun, 2019 Apr 16. PMID 30837153
    3. A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway. Collins RT, et al. Genetics, 2005 May. PMID 15744048, Free PMC Article
    4. Msl1-mediated dimerization of the dosage compensation complex is essential for male X-chromosome regulation in Drosophila. Hallacli E, et al. Mol Cell, 2012 Nov 30. PMID 23084835
    5. In Depth Exploration of the Alternative Proteome of Drosophila melanogaster. Fabre B, et al. Front Cell Dev Biol, 2022. PMID 35721519, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15011-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4255991..4259152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139622.1 → NP_647879.1  uncharacterized protein Dmel_CG15011 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647879.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q52KA5, Q9VZF2
      Related
      FBpp0073100, FBtr0073244
      Conserved Domains (1) summary
      cd06008
      Location:426 → 474
      NF-X1-zinc-finger; Presumably a zinc binding domain, which has been shown to bind to DNA in the human nuclear transcriptional repressor NF-X1. The zinc finger can be characterized by the pattern C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C. The NF-X1 zinc finger ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZF2 Q9VZF2

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