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    Muc68D Mucin 68D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Muc68Dprovided by FlyBase
    Official Full Name
    Mucin 68Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036203
    Locus tag
    Dmel_CG6004
    See related
    AllianceGenome:FB:FBgn0036203
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0153538.47; anon-WO0153538.48; CG6004; Dmel\CG6004
    Summary
    Predicted to be an extracellular matrix structural constituent. Predicted to be located in extracellular matrix. Is expressed in embryonic/larval gut; embryonic/larval salivary gland; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Muc68D in Genome Data Viewer
    Location:
    68D4-68D4; 3-36 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11767299..11772157, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11760399..11765257, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lost and found Neighboring gene Gustatory receptor 68a Neighboring gene mir-314 stem loop Neighboring gene mir-956 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system. Kim K, et al. Proc Natl Acad Sci U S A, 2020 May 12. PMID 32345720, Free PMC Article
    2. Hazard Assessment of the Effects of Acute and Chronic Exposure to Permethrin, Copper Hydroxide, Acephate, and Validamycin Nanopesticides on the Physiology of Drosophila: Novel Insights into the Cellular Internalization and Biological Effects. Demir E, et al. Int J Mol Sci, 2022 Aug 14. PMID 36012388, Free PMC Article
    3. Antigenotoxic potential of boron nitride nanotubes. Demir E, et al. Nanotoxicology, 2018 Oct. PMID 29952680
    4. Are bioplastics safe? Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila. Alaraby M, et al. Sci Total Environ, 2024 Apr 1. PMID 38354814
    5. Cellular and molecular organization of the Drosophila foregut. Zhu H, et al. Proc Natl Acad Sci U S A, 2024 Mar 12. PMID 38442150, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables extracellular matrix structural constituent ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mucin 68D
    Names
    CG6004-PB
    Muc68D-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11767299..11772157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140247.3 → NP_648504.2  mucin 68D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648504.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY55, Q9VTN2
      Conserved Domains (3) summary
      smart00494
      Location:1459 → 1505
      ChtBD2; Chitin-binding domain type 2
      PHA03249
      Location:1088 → 1209
      PHA03249; DNA packaging tegument protein UL25; Provisional
      pfam01607
      Location:1388 → 1440
      CBM_14; Chitin binding Peritrophin-A domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTN2 Q9VTN2

    Gene LinkOut

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