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    CG7402 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39994, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7402provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036768
    Locus tag
    Dmel_CG7402
    See related
    AllianceGenome:FB:FBgn0036768
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7402
    Summary
    Predicted to enable sulfuric ester hydrolase activity. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to several human genes including ARSB (arylsulfatase B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7402 in Genome Data Viewer
    Location:
    75A8-75A8; 3-45 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17887705..17891404)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17880805..17884504)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 74F Neighboring gene prestin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. There are two distinct arylsulfatase activities in Drosophila. Pelliccia JG, et al. Biochem Genet, 1987 Aug. PMID 3447585
    2. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Jansen IE, et al. Genome Biol, 2017 Jan 30. PMID 28137300, Free PMC Article
    3. A comprehensive study of genic variation in natural populations of Drosophila melanogaster. VI. Patterns and processes of genic divergence between D. melanogaster and its sibling species, Drosophila simulans. Choudhary M, et al. Genetics, 1992 Apr. PMID 1582561, Free PMC Article
    4. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article
    5. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sulfuric ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sulfuric ester hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7402-PA
    NP_649023.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17887705..17891404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140766.3 → NP_649023.1  uncharacterized protein Dmel_CG7402 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649023.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVM4
      Related
      FBpp0074909
      Conserved Domains (2) summary
      PRK13759
      Location:25 → 459
      PRK13759; arylsulfatase; Provisional
      cd16029
      Location:28 → 436
      4-S; N-acetylgalactosamine 4-sulfatase, also called arylsulftase B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVM4 Q9VVM4

    Gene LinkOut

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