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    CG32137 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39537, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32137provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052137
    Locus tag
    Dmel_CG32137
    See related
    AllianceGenome:FB:FBgn0052137
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    32137; CG17365; CG17366; Dmel\CG32137
    Summary
    Enables cargo adaptor activity. Involved in chaeta development and protein transport along microtubule. Predicted to be active in cytosol. Is expressed in several structures, including amnioserosa; dorsal pharyngeal muscle cell; embryonic head sensory system; gut section; and sense organ. Orthologous to several human genes including BICDL1 (BICD family like cargo adaptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32137 in Genome Data Viewer
    Location:
    70C6-70C7; 3-41 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13939250..13962647)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13932350..13955747)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dynactin 1, p150 subunit Neighboring gene Meiotic central spindle Neighboring gene short spindle 2 Neighboring gene Nuclear export factor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of BicDR in bristle shaft construction and support of BicD functions. Jejina A, et al. J Cell Sci, 2024 Jan 15. PMID 38264934, Free PMC Article
    2. Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control. Siller KH, et al. Mol Biol Cell, 2005 Nov. PMID 16107559, Free PMC Article
    3. Alcohol sensitivity in Drosophila: translational potential of systems genetics. Morozova TV, et al. Genetics, 2009 Oct. PMID 19652175, Free PMC Article
    4. Glial and neuronal functions of the Drosophila homolog of the human SWI/SNF gene ATR-X (DATR-X) and the jing zinc-finger gene specify the lateral positioning of longitudinal glia and axons. Sun X, et al. Genetics, 2006 Jul. PMID 16648585, Free PMC Article
    5. Modulation of the activity of a polycomb-group response element in Drosophila by a mutation in the transcriptional activator woc. Noyes A, et al. G3 (Bethesda), 2011 Nov. PMID 22384357, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Role of BicDR in bristle shaft construction and support of BicD functions.
      Title: Role of BicDR in bristle shaft construction and support of BicD functions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cargo adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaeta development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein transport along microtubule IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32137-PA
    CG32137-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13939250..13962647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168563.2 → NP_729935.1  uncharacterized protein Dmel_CG32137, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729935.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SWR2, Q9VUA2, Q9VUA3
      UniProtKB/TrEMBL
      Q8IGY6
      Related
      FBpp0075500
      Conserved Domains (1) summary
      pfam14235
      Location:105 → 172
      DUF4337; Domain of unknown function (DUF4337)

    2. NM_168564.2 → NP_729936.1  uncharacterized protein Dmel_CG32137, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729936.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGY6
      Related
      FBpp0075499
      Conserved Domains (1) summary
      TIGR02168
      Location:14 → 238
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IGY6 Q8IGY6
    Q8SWR2.1 Q8SWR2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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