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    Ir68b Ionotropic receptor 68b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39378, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir68bprovided by FlyBase
    Official Full Name
    Ionotropic receptor 68bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036250
    Locus tag
    Dmel_CG17152
    See related
    AllianceGenome:FB:FBgn0036250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    68b; CG17152; CT38092; DmelIR68b; Dmel\CG17152; IR68b
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in larval abdomen. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir68b in Genome Data Viewer
    Location:
    68F4-68F4; 3-38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12125487..12127394, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12118587..12120494, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ypsilon schachtel Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR11538 Neighboring gene Larval serum protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Dm-Myb Oncoprotein Contributes to Insulator Function and Stabilizes Repressive H3K27me3 PcG Domains. Santana JF, et al. Cell Rep, 2020 Mar 10. PMID 32160531, Free PMC Article
    2. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Lee JY, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2009 Nov. PMID 19695344
    3. An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Sánchez-Alcañiz JA, et al. Nat Commun, 2018 Oct 12. PMID 30315166, Free PMC Article
    4. The Structure and Function of Ionotropic Receptors in Drosophila. Ni L. Front Mol Neurosci, 2020. PMID 33597847, Free PMC Article
    5. Ion channels and synaptic organization: analysis of the Drosophila genome. Littleton JT, et al. Neuron, 2000 Apr. PMID 10798390

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 68b
    Names
    CG17152-PA
    Ir68b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12125487..12127394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140291.1 → NP_648548.1  ionotropic receptor 68b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648548.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTT6
      Related
      FBpp0075758, FBtr0076026
      Conserved Domains (1) summary
      pfam00060
      Location:333 → 607
      Lig_chan; Ligand-gated ion channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTT6 Q9VTT6

    Gene LinkOut

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