Bet3 Blocked early in transport 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Bet3provided by FlyBase
Official Full Name: Blocked early in transport 3provided by FlyBase
Primary source: FLYBASE:FBgn0260859
Locus tag: Dmel_CG3911
See related: AllianceGenome:FB:FBgn0260859
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BET3; Bet3p; CG3911; dBet3; Dmel\CG3911; TRAPPC3
Summary: Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in dsRNA transport and protein secretion. Located in Golgi apparatus. Part of TRAPPII protein complex and TRAPPIII protein complex. Is expressed in adult head and adult heart. Orthologous to several human genes including TRAPPC3 (trafficking protein particle complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (9438482..9442267, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (9431582..9435367, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to guanyl-nucleotide exchange factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in Golgi vesicle transport	IC Inferred by Curator more info	PubMed
involved_in Golgi vesicle transport	IEA Inferred from Electronic Annotation more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intra-Golgi vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein secretion	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
part_of TRAPP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TRAPP complex	IEA Inferred from Electronic Annotation more info
part_of TRAPP complex	ISS Inferred from Sequence or Structural Similarity more info
part_of TRAPPII protein complex	IDA Inferred from Direct Assay more info	PubMed
part_of TRAPPIII protein complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in cis-Golgi network membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

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