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    CG30349 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35885, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG30349provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050349
    Locus tag
    Dmel_CG30349
    See related
    AllianceGenome:FB:FBgn0050349
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13750; CG2396; Dmel\CG30349
    Summary
    Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in nucleolus. Is expressed in several structures, including adult head; anal pad primordium; anterior endoderm; dorsal pharyngeal muscle cell; and embryonic/larval midgut primordium. Orthologous to human WDR43 (WD repeat domain 43). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30349 in Genome Data Viewer
    Location:
    44F5-44F6; 2-59 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8907518..8910885)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4795023..4798390)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene G protein gamma subunit 1 Neighboring gene Chaperonin containing TCP1 subunit 8 Neighboring gene uncharacterized protein Neighboring gene Phosphoglucose isomerase Neighboring gene lines Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth. Furrer M, et al. J Biol Chem, 2010 Dec 17. PMID 20937797, Free PMC Article
    2. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    3. Combinatorial binding leads to diverse regulatory responses: Lmd is a tissue-specific modulator of Mef2 activity. Cunha PM, et al. PLoS Genet, 2010 Jul 1. PMID 20617173, Free PMC Article
    4. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
    5. Adaptation to Chronic Nutritional Stress Leads to Reduced Dependence on Microbiota in Drosophila melanogaster. Erkosar B, et al. mBio, 2017 Oct 24. PMID 29066546, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30349-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8907518..8910885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136577.2 → NP_610421.1  uncharacterized protein Dmel_CG30349 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610421.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7K2, Q8SXT6
      Related
      FBpp0087731
      Conserved Domains (4) summary
      COG2319
      Location:7 → 237
      WD40; WD40 repeat [General function prediction only]
      pfam04003
      Location:439 → 534
      Utp12; Dip2/Utp12 Family
      sd00039
      Location:7 → 50
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:11 → 230
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z7K2 A1Z7K2
    Q8SXT6 Q8SXT6

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