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    HA5 plasma membrane H+-ATPase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816988, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HA5
    Official Full Name
    plasma membrane H+-ATPase
    Primary source
    TAIR:AT2G24520
    Locus tag
    AT2G24520
    See related
    Araport:AT2G24520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AHA5; F25P17.18; F25P17_18; H(+)-ATPase 5
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    Genomic context

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    See HA5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Sequence:
    Chromosome: 2; NC_003071.7 (10414963..10420029)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene transcriptional regulator of RNA polII, SAGA, subunit Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis Plasma Membrane ATPase AHA5 Is Negatively Involved in PAMP-Triggered Immunity. Zhao Z, et al. Int J Mol Sci, 2022 Mar 31. PMID 35409217, Free PMC Article
    2. Auxin Influx Carrier AUX1 Confers Acid Resistance for Arabidopsis Root Elongation Through the Regulation of Plasma Membrane H+-ATPase. Inoue SI, et al. Plant Cell Physiol, 2016 Oct. PMID 27503216, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis Plasma Membrane ATPase AHA5 Is Negatively Involved in PAMP-Triggered Immunity.
      Title: Arabidopsis Plasma Membrane ATPase AHA5 Is Negatively Involved in PAMP-Triggered Immunity.
    2. AUX1 positively regulates the plasma membrane H(+)-ATPase activity through maintenance of the auxin accumulation in root tips, and this process may serve to maintain root elongation especially under low pH conditions.
      Title: Auxin Influx Carrier AUX1 Confers Acid Resistance for Arabidopsis Root Elongation Through the Regulation of Plasma Membrane H+-ATPase.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001335933.1
    NM_001335935.1
    NM_128013.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables P-type proton-exporting transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plasma membrane H+-ATPase
    NP_001318282.1
    • H(+)-ATPase 5 (HA5); FUNCTIONS IN: ATPase activity; INVOLVED IN: cation transport, metabolic process, ATP biosynthetic process; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, plasma-membrane proton-efflux (InterPro:IPR006534), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: H(+)-ATPase 2 (TAIR:AT4G30190.1); Has 37354 Blast hits to 32806 proteins in 3183 species: Archae - 691; Bacteria - 24060; Metazoa - 3886; Fungi - 2499; Plants - 1868; Viruses - 3; Other Eukaryotes - 4347 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10414963..10420029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335934.1 → NP_001325336.1  plasma membrane H+-ATPase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IPQ2, Q9SJB3
      UniProtKB/TrEMBL
      A0A1P8B2Y6

    2. NM_001335933.1 → NP_001318282.1  plasma membrane H+-ATPase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IPQ2, Q9SJB3
      UniProtKB/TrEMBL
      A0A1P8B2U9

    3. NM_128013.2 → NP_180028.1  plasma membrane H+-ATPase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180028.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IPQ2, Q9SJB3
      UniProtKB/TrEMBL
      A0A1P8B2U9
      Conserved Domains (5) summary
      smart00831
      Location:1 → 65
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      COG4087
      Location:543 → 613
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01647
      Location:14 → 786
      ATPase-IIIA_H; plasma-membrane proton-efflux P-type ATPase
      pfam00122
      Location:79 → 300
      E1-E2_ATPase; E1-E2 ATPase
      pfam13246
      Location:354 → 415
      Cation_ATPase; Cation transport ATPase (P-type)

    4. NM_001335935.1 → NP_001325337.1  plasma membrane H+-ATPase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2V0
    Nucleotide Protein
    Heading Accession and Version

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