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    NUDX15 nudix hydrolase homolog 15 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839773, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NUDX15
    Official Full Name
    nudix hydrolase homolog 15
    Primary source
    TAIR:AT1G28960
    Locus tag
    AT1G28960
    See related
    Araport:AT1G28960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 15; ATNUDT15; ATNUDX15; F1K23.5; F1K23_5; nudix hydrolase homolog 15
    Summary
    Encodes a ppGpp pyrophosphohydrolase.
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    Genomic context

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    See NUDX15 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (10109500..10111738, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene tRNA-Pro Neighboring gene tRNA-Pro Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene reverse transcriptase zinc-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A comparative analysis of the molecular characteristics of the Arabidopsis CoA pyrophosphohydrolases AtNUDX11, 15, and 15a. Ito D, et al. Biosci Biotechnol Biochem, 2012. PMID 22232253
    2. Enzymatic and molecular characterization of Arabidopsis ppGpp pyrophosphohydrolase, AtNUDX26. Ito D, et al. Biosci Biotechnol Biochem, 2012. PMID 23221701
    3. Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis. Ogawa T, et al. Plant Physiol, 2008 Nov. PMID 18815383, Free PMC Article
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. comparative studies of the gene regulation, the kinetic parameters, and the intracellular localization of AtNUDX11, 15, and 15a
      Title: A comparative analysis of the molecular characteristics of the Arabidopsis CoA pyrophosphohydrolases AtNUDX11, 15, and 15a.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036027.2
    NM_102640.3
    NM_179394.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables coenzyme A diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within coenzyme A biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within nucleoside phosphate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within succinyl-CoA metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nudix hydrolase homolog 15
    NP_001031104.1
    • nudix hydrolase homolog 15 (NUDX15); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase domain (InterPro:IPR000086), NUDIX hydrolase, AtNUDT22 (InterPro:IPR017397); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 22 (TAIR:AT2G33980.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_564316.1
    • nudix hydrolase homolog 15 (NUDX15); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase domain (InterPro:IPR000086), NUDIX hydrolase, AtNUDT22 (InterPro:IPR017397); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 22 (TAIR:AT2G33980.1); Has 3635 Blast hits to 3634 proteins in 1300 species: Archae - 59; Bacteria - 2277; Metazoa - 167; Fungi - 181; Plants - 103; Viruses - 0; Other Eukaryotes - 848 (source: NCBI BLink).
    NP_849725.2
    • nudix hydrolase homolog 15 (NUDX15); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase domain (InterPro:IPR000086), NUDIX hydrolase, AtNUDT22 (InterPro:IPR017397); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 22 (TAIR:AT2G33980.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10109500..10111738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179393.4 → NP_849724.1  nudix hydrolase homolog 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849724.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WKX6, Q3E701, Q3E702, Q67YK3, Q8GYB1, Q9SHQ7
      UniProtKB/TrEMBL
      A0A5S9WB78
      Conserved Domains (1) summary
      cl00447
      Location:97 → 280
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    2. NM_001332826.1 → NP_001320887.1  nudix hydrolase homolog 15 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WKX6, Q3E701, Q3E702, Q67YK3, Q8GYB1, Q9SHQ7
      UniProtKB/TrEMBL
      A0A5S9WB78
      Conserved Domains (1) summary
      cl00447
      Location:97 → 280
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    3. NM_001036027.2 → NP_001031104.1  nudix hydrolase homolog 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031104.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WAX9, A0A5S9WB78
      Conserved Domains (1) summary
      cl00447
      Location:97 → 280
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    4. NM_102640.3 → NP_564316.1  nudix hydrolase homolog 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564316.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WAX9, A0A5S9WB78
      Conserved Domains (1) summary
      cl00447
      Location:97 → 280
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    5. NM_179394.3 → NP_849725.2  nudix hydrolase homolog 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849725.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WAX9, A0A5S9WB78
      Conserved Domains (1) summary
      cl00447
      Location:97 → 280
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GYB1.2

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