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    TRPV4 transient receptor potential cation channel subfamily V member 4 [ Homo sapiens (human) ]

    Gene ID: 59341, updated on 10-Dec-2024

    Summary

    Official Symbol
    TRPV4provided by HGNC
    Official Full Name
    transient receptor potential cation channel subfamily V member 4provided by HGNC
    Primary source
    HGNC:HGNC:18083
    See related
    Ensembl:ENSG00000111199 MIM:605427; AllianceGenome:HGNC:18083
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SMAL; VRL2; BCYM3; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1
    Summary
    This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
    Expression
    Broad expression in kidney (RPKM 5.7), salivary gland (RPKM 3.0) and 14 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TRPV4 in Genome Data Viewer
    Location:
    12q24.11
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (109783087..109833398, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (109758559..109808862, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (110220892..110271203, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr12:110105927-110106096 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:110108888-110110087 Neighboring gene RN7SK pseudogene 250 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110133637-110134446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:110150092-110150655 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4842 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4843 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110164162-110164872 Neighboring gene family with sequence similarity 222 member A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110169301-110169801 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110174581-110175080 Neighboring gene FAM222A antisense RNA 1 Neighboring gene HNF1 motif-containing MPRA enhancer 206 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110177165-110177666 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110177667-110178166 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:110209881-110210380 Neighboring gene Sharpr-MPRA regulatory region 11384 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:110258983-110259483 Neighboring gene uncharacterized LOC105369975 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4844 Neighboring gene microRNA 4497 Neighboring gene glycolipid transfer protein Neighboring gene RNA, 7SL, cytoplasmic 441, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Avascular necrosis of femoral head, primary, 2 not available
    Brachyrachia (short spine dysplasia) not available
    Charcot-Marie-Tooth disease axonal type 2C not available
    Familial digital arthropathy-brachydactyly not available
    Metatropic dysplasia not available
    Neuronopathy, distal hereditary motor, autosomal dominant 8 not available
    Parastremmatic dwarfism not available
    Scapuloperoneal spinal muscular atrophy not available
    Sodium serum level quantitative trait locus 1
    MedGen: C3150755 OMIM: 613508 GeneReviews: Not available
    not available
    Spondyloepimetaphyseal dysplasia, Maroteaux type not available
    Spondylometaphyseal dysplasia, Kozlowski type not available

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables SH2 domain binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables actin filament binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables alpha-tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables beta-tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables calcium channel activity TAS
    Traceable Author Statement
    more info
     
    enables calmodulin binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables monoatomic cation channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables osmosensor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase C binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables stretch-activated, monoatomic cation-selective, calcium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in actin filament organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in blood vessel endothelial cell delamination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in calcium ion import ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in calcium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in calcium ion import into cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in calcium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in calcium ion transmembrane transport TAS
    Traceable Author Statement
    more info
     
    involved_in calcium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in calcium ion transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in cartilage development involved in endochondral bone morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell volume homeostasis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cell-cell junction assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular hypotonic response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular hypotonic response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular hypotonic salinity response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to heat ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to osmotic stress ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cortical microtubule organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in diet induced thermogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hyperosmotic salinity response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular calcium ion homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in microtubule polymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in multicellular organismal-level water homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of brown fat cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in osmosensory signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in osmosensory signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in osmosensory signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of chemokine (C-C motif) ligand 5 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of chemokine (C-X-C motif) ligand 1 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of cytosolic calcium ion concentration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of interleukin-6 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of macrophage chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of macrophage inflammatory protein 1 alpha production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of microtubule depolymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of monocyte chemotactic protein-1 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of striated muscle contraction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of vascular permeability IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of aerobic respiration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of response to osmotic stress IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to insulin IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to mechanical stimulus TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in vasopressin secretion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in adherens junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cortical actin cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    colocalizes_with cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in filopodium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in focal adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in growth cone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in lamellipodium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in ruffle membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    transient receptor potential cation channel subfamily V member 4
    Names
    OSM9-like transient receptor potential channel 4
    osm-9-like TRP channel 4
    osmosensitive transient receptor potential channel 4
    transient receptor potential protein 12
    vanilloid receptor-like channel 2
    vanilloid receptor-related osmotically activated channel

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_017090.1 RefSeqGene

      Range
      5001..55321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_372

    mRNA and Protein(s)

    1. NM_001177428.1NP_001170899.1  transient receptor potential cation channel subfamily V member 4 isoform e

      See identical proteins and their annotated locations for NP_001170899.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.
      Source sequence(s)
      AB032427, AC007834, DA869138, DQ059644
      Consensus CDS
      CCDS53828.1
      UniProtKB/Swiss-Prot
      Q9HBA0
      Related
      ENSP00000442167.1, ENST00000541794.5
      Conserved Domains (5) summary
      cd00204
      Location:236343
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:511683
      Ion_trans; Ion transport protein
      pfam09685
      Location:502548
      DUF4870; Domain of unknown function (DUF4870)
      pfam12796
      Location:242347
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:191231
      ANK; ANK repeat [structural motif]
    2. NM_001177431.1NP_001170902.1  transient receptor potential cation channel subfamily V member 4 isoform d

      See identical proteins and their annotated locations for NP_001170902.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks a segment in the 5' coding region coding region, compared to variant 1. The encoded isoform (d) is shorter, compared to isoform a.
      Source sequence(s)
      AB032427, AC007834, AF279673, DQ059645
      Consensus CDS
      CCDS53829.1
      UniProtKB/Swiss-Prot
      Q9HBA0
      Related
      ENSP00000444336.1, ENST00000536838.1
      Conserved Domains (5) summary
      cd00204
      Location:204356
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:524696
      Ion_trans; Ion transport protein
      pfam09685
      Location:515561
      DUF4870; Domain of unknown function (DUF4870)
      pfam12796
      Location:255360
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:203234
      ANK; ANK repeat [structural motif]
    3. NM_001177433.1NP_001170904.1  transient receptor potential cation channel subfamily V member 4 isoform c

      See identical proteins and their annotated locations for NP_001170904.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks two in-frame exons in the coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.
      Source sequence(s)
      AB032427, BC143315, DQ059646
      Consensus CDS
      CCDS53827.1
      UniProtKB/Swiss-Prot
      Q9HBA0
      Related
      ENSP00000443611.1, ENST00000544971.5
      Conserved Domains (4) summary
      cd00204
      Location:236336
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:149692
      trp; transient-receptor-potential calcium channel protein
      pfam09685
      Location:442488
      DUF4870; Domain of unknown function (DUF4870)
      sd00045
      Location:191231
      ANK; ANK repeat [structural motif]
    4. NM_021625.5NP_067638.3  transient receptor potential cation channel subfamily V member 4 isoform a

      See identical proteins and their annotated locations for NP_067638.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC007834, AJ296305
      Consensus CDS
      CCDS9134.1
      UniProtKB/Swiss-Prot
      B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0
      Related
      ENSP00000261740.2, ENST00000261740.7
      Conserved Domains (5) summary
      cd00204
      Location:238390
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:558730
      Ion_trans; Ion transport protein
      pfam09685
      Location:549595
      DUF4870; Domain of unknown function (DUF4870)
      pfam12796
      Location:289394
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:237268
      ANK; ANK repeat [structural motif]
    5. NM_147204.2NP_671737.1  transient receptor potential cation channel subfamily V member 4 isoform b

      See identical proteins and their annotated locations for NP_671737.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in an isoform (b) that lacks an internal segment compared to isoform a.
      Source sequence(s)
      AB032427, AB073669, AC007834, BC143315
      Consensus CDS
      CCDS9135.1
      UniProtKB/Swiss-Prot
      Q9HBA0
      Related
      ENSP00000442738.1, ENST00000537083.5
      Conserved Domains (4) summary
      cd00204
      Location:238383
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:149739
      trp; transient-receptor-potential calcium channel protein
      pfam09685
      Location:489535
      DUF4870; Domain of unknown function (DUF4870)
      sd00045
      Location:237268
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      109783087..109833398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047429295.1XP_047285251.1  transient receptor potential cation channel subfamily V member 4 isoform X9

    2. XM_047429293.1XP_047285249.1  transient receptor potential cation channel subfamily V member 4 isoform X5

    3. XM_047429294.1XP_047285250.1  transient receptor potential cation channel subfamily V member 4 isoform X7

    4. XM_017019774.2XP_016875263.1  transient receptor potential cation channel subfamily V member 4 isoform X3

      UniProtKB/Swiss-Prot
      B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0
      Conserved Domains (5) summary
      cd00204
      Location:238390
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:558730
      Ion_trans; Ion transport protein
      pfam09685
      Location:549595
      DUF4870; Domain of unknown function (DUF4870)
      pfam12796
      Location:289394
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:237268
      ANK; ANK repeat [structural motif]
    5. XM_011538633.3XP_011536935.2  transient receptor potential cation channel subfamily V member 4 isoform X6

    6. XM_011538631.3XP_011536933.2  transient receptor potential cation channel subfamily V member 4 isoform X2

    7. XM_011538632.3XP_011536934.2  transient receptor potential cation channel subfamily V member 4 isoform X4

    8. XM_011538630.3XP_011536932.2  transient receptor potential cation channel subfamily V member 4 isoform X1

    9. XM_011538634.3XP_011536936.2  transient receptor potential cation channel subfamily V member 4 isoform X8

    10. XM_011538635.3XP_011536937.1  transient receptor potential cation channel subfamily V member 4 isoform X10

      Conserved Domains (2) summary
      TIGR00870
      Location:200682
      trp; transient-receptor-potential calcium channel protein
      sd00045
      Location:288319
      ANK; ANK repeat [structural motif]
    11. XM_047429296.1XP_047285252.1  transient receptor potential cation channel subfamily V member 4 isoform X11

      UniProtKB/TrEMBL
      F5H6Q4
      Related
      ENSP00000437449.1, ENST00000538125.5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      109758559..109808862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054372806.1XP_054228781.1  transient receptor potential cation channel subfamily V member 4 isoform X9

    2. XM_054372802.1XP_054228777.1  transient receptor potential cation channel subfamily V member 4 isoform X5

    3. XM_054372804.1XP_054228779.1  transient receptor potential cation channel subfamily V member 4 isoform X7

    4. XM_054372800.1XP_054228775.1  transient receptor potential cation channel subfamily V member 4 isoform X3

      UniProtKB/Swiss-Prot
      B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0
    5. XM_054372803.1XP_054228778.1  transient receptor potential cation channel subfamily V member 4 isoform X6

    6. XM_054372799.1XP_054228774.1  transient receptor potential cation channel subfamily V member 4 isoform X2

    7. XM_054372801.1XP_054228776.1  transient receptor potential cation channel subfamily V member 4 isoform X4

    8. XM_054372798.1XP_054228773.1  transient receptor potential cation channel subfamily V member 4 isoform X1

    9. XM_054372805.1XP_054228780.1  transient receptor potential cation channel subfamily V member 4 isoform X8

    10. XM_054372807.1XP_054228782.1  transient receptor potential cation channel subfamily V member 4 isoform X10

    11. XM_054372808.1XP_054228783.1  transient receptor potential cation channel subfamily V member 4 isoform X11

      UniProtKB/TrEMBL
      F5H6Q4