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    Gprin2 G protein regulated inducer of neurite outgrowth 2 [ Mus musculus (house mouse) ]

    Gene ID: 432839, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Gprin2provided by MGI
    Official Full Name
    G protein regulated inducer of neurite outgrowth 2provided by MGI
    Primary source
    MGI:MGI:2444560
    See related
    Ensembl:ENSMUSG00000071531 AllianceGenome:MGI:2444560
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm286; mKIAA0514; C230073P13; C130040D06Rik
    Summary
    Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. Is expressed in amygdala and brain. Orthologous to human GPRIN2 (G protein regulated inducer of neurite outgrowth 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 2.6), whole brain E14.5 (RPKM 2.3) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gprin2 in Genome Data Viewer
    Location:
    14 B; 14 20.8 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (33907645..33923649, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (34185688..34201692, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L23A, pseudogene 3 Neighboring gene BRCA1/BRCA2-containing complex, subunit 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36364 Neighboring gene VISTA enhancer mm340 Neighboring gene synaptotagmin XV Neighboring gene shieldin complex subunit 2 Neighboring gene STARR-seq mESC enhancer starr_36366 Neighboring gene zinc finger, DHHC domain containing 17 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Maternal high-fat diet-induced microbiota changes are associated with alterations in embryonic brain metabolites and adolescent behaviour. Ratsika A, et al. Brain Behav Immun, 2024 Oct. PMID 39032541
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G protein-regulated inducer of neurite outgrowth 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183209.3 → NP_899032.2  G protein-regulated inducer of neurite outgrowth 2

      See identical proteins and their annotated locations for NP_899032.2

      Status: VALIDATED

      Source sequence(s)
      AC154738
      Consensus CDS
      CCDS49443.1
      UniProtKB/TrEMBL
      A0A2I3BRN2
      Related
      ENSMUSP00000154640.2, ENSMUST00000226613.2
      Conserved Domains (1) summary
      pfam15235
      Location:347 → 447
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      33907645..33923649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519212.2 → XP_006519275.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

      See identical proteins and their annotated locations for XP_006519275.1

      UniProtKB/TrEMBL
      A0A2I3BRN2
      Conserved Domains (1) summary
      pfam15235
      Location:347 → 447
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

    2. XM_006519213.5 → XP_006519276.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

      See identical proteins and their annotated locations for XP_006519276.1

      UniProtKB/TrEMBL
      A0A2I3BRN2
      Conserved Domains (1) summary
      pfam15235
      Location:347 → 447
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

    3. XM_011245111.1 → XP_011243413.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

      See identical proteins and their annotated locations for XP_011243413.1

      UniProtKB/TrEMBL
      A0A2I3BRN2
      Conserved Domains (1) summary
      pfam15235
      Location:347 → 447
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

    4. XM_006519215.5 → XP_006519278.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

      See identical proteins and their annotated locations for XP_006519278.1

      UniProtKB/TrEMBL
      A0A2I3BRN2
      Conserved Domains (1) summary
      pfam15235
      Location:347 → 447
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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