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    Cpn60alpha2 TCP-1/cpn60 chaperonin family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832000, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Cpn60alpha2
    Official Full Name
    TCP-1/cpn60 chaperonin family protein
    Primary source
    TAIR:AT5G18820
    Locus tag
    AT5G18820
    See related
    Araport:AT5G18820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chaperonin-60alpha2; EMB3007; embryo defective 3007; F17K4.70; F17K4_70
    Summary
    Encodes a subunit of chloroplasts chaperonins that are involved in mediating the folding of newly synthesized, translocated, or stress-denatured proteins. Cpn60 subunits are: Cpn60alpha1 (At2g28000), AtCpn60alpha2 (At5g18820), AtCpn60beta1 (At1g55490), AtCpn60beta2 (At3g13470), AtCpn60beta3 (At5g56500), AtCpn60beta4 (At1g26230).
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    Genomic context

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    See Cpn60alpha2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (6271386..6274599)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Cox19-like CHCH family protein Neighboring gene SC35-like splicing factor 28 Neighboring gene squamosa promoter binding protein-like 7 Neighboring gene Major facilitator superfamily protein Neighboring gene Low-density receptor-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional divergence of chloroplast Cpn60α subunits during Arabidopsis embryo development. Ke X, et al. PLoS Genet, 2017 Sep. PMID 28961247, Free PMC Article
    2. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    3. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001343572.1
    NM_121887.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TCP-1/cpn60 chaperonin family protein
    NP_197383.1
    • embryo defective 3007 (EMB3007); FUNCTIONS IN: ATP binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: chaperonin-60alpha (TAIR:AT2G28000.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6271386..6274599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343571.1 → NP_001330414.1  TCP-1/cpn60 chaperonin family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UNC4, A0A1P8BAS2

    2. NM_121887.3 → NP_197383.1  TCP-1/cpn60 chaperonin family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197383.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56XV8
      UniProtKB/TrEMBL
      A0A178UNC4, A0A5S9Y5B6, A0A654G296
      Conserved Domains (1) summary
      cd03344
      Location:36 → 557
      GroEL; GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found ...

    3. NM_001343572.1 → NP_001330413.1  TCP-1/cpn60 chaperonin family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAR0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56XV8.1

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