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    FATB fatty acyl-ACP thioesterases B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837372, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FATB
    Official Full Name
    fatty acyl-ACP thioesterases B
    Primary source
    TAIR:AT1G08510
    Locus tag
    AT1G08510
    See related
    Araport:AT1G08510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    fatty acyl-ACP thioesterases B; T27G7.19; T27G7_19
    Summary
    Encodes an acyl-acyl carrier protein thioesterase. Hydrolyzes primarily saturated acyl-ACPs with chain lengths that vary between 8 and 18 carbons. Involved in saturated fatty acid synthesis. Nuclear-encoded, plastid-targeted globular protein that is functional as dimer.
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    Genomic context

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    See FATB in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (2691062..2694547, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase subunit Neighboring gene chloroplastic NIFS-like cysteine desulfurase Neighboring gene early nodulin-like protein 18 Neighboring gene ALBINA 1 Neighboring gene chitinase-like protein Neighboring gene RNApolymerase sigma subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of the FATB gene in Arabidopsis demonstrates an essential role of saturated fatty acids in plant growth. Bonaventure G, et al. Plant Cell, 2003 Apr. PMID 12671095, Free PMC Article
    2. Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants. Branham SE, et al. J Hered, 2016 May. PMID 26865732, Free PMC Article
    3. Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases. Salas JJ, et al. Arch Biochem Biophys, 2002 Jul 1. PMID 12061798
    4. A structural model of the plant acyl-acyl carrier protein thioesterase FatB comprises two helix/4-stranded sheet domains, the N-terminal domain containing residues that affect specificity and the C-terminal domain containing catalytic residues. Mayer KM, et al. J Biol Chem, 2005 Feb 4. PMID 15531590
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FAD2 and FATB may have influenced the adaptive evolution of seed oil composition to optimize seed oil melting point relative to germination temperatures
      Title: Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_100724.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acyl carrier activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables fatty acyl-[ACP] hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fatty acyl-ACP thioesterases B
    NP_172327.1
    • fatty acyl-ACP thioesterases B (FATB); CONTAINS InterPro DOMAIN/s: Acyl-ACP-thioesterase, N-terminal domain (InterPro:IPR021113), Acyl-ACP thioesterase (InterPro:IPR002864); BEST Arabidopsis thaliana protein match is: fatA acyl-ACP thioesterase (TAIR:AT3G25110.1); Has 1275 Blast hits to 1274 proteins in 533 species: Archae - 0; Bacteria - 944; Metazoa - 0; Fungi - 0; Plants - 322; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2691062..2694547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100724.3 → NP_172327.1  fatty acyl-ACP thioesterases B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172327.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42558, Q42562, Q9SJE2
      UniProtKB/TrEMBL
      A0A178W8J1, A0A5S9TC41, A0A654E7X4
      Conserved Domains (1) summary
      PLN02370
      Location:1 → 412
      PLN02370; acyl-ACP thioesterase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJE2.1

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