PBE1 20S proteasome beta subunit E1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PBE1
Official Full Name: 20S proteasome beta subunit E1
Primary source: TAIR:AT1G13060
Locus tag: AT1G13060
See related: Araport:AT1G13060
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 20S proteasome beta subunit E1; 20S PROTEASOME BETA SUBUNIT PBE1; F3F19.8; F3F19_8
Summary: Encodes 20S proteasome beta subunit PBE1 (PBE1).
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Genomic context

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See PBE1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 9

Sequence:: Chromosome: 1; NC_003070.9 (4452190..4454900)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PBE1-mediated intact proteasome assembly is essential for successful autotrophic growth.
Title: The β5 subunit is essential for intact 26S proteasome assembly to specifically promote plant autotrophic growth under salt stress.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001198049.1

Supported by ESTs:

NM_001332061.1

Supported by ESTs:

NM_101176.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Process	Evidence Code	Pubs
involved_in proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
located_in extracellular region	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
part_of proteasome complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex	TAS Traceable Author Statement more info	PubMed
part_of proteasome core complex, beta-subunit complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: 20S proteasome beta subunit E1

NP_001184978.1

20S proteasome beta subunit E1 (PBE1); FUNCTIONS IN: peptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: guard cell, pollen tube; EXPRESSED DURING: seed development stages; CONTAINS InterPro DOMAIN/s: Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G26340.1).

NP_172765.1

20S proteasome beta subunit E1 (PBE1); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: response to cadmium ion, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: guard cell, cultured cell, pollen tube, leaf; EXPRESSED DURING: seed development stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G26340.1); Has 6463 Blast hits to 6458 proteins in 614 species: Archae - 814; Bacteria - 515; Metazoa - 2076; Fungi - 1348; Plants - 839; Viruses - 0; Other Eukaryotes - 871 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

4452190..4454900

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101176.3 → NP_172765.1 20S proteasome beta subunit E1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172765.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O23717, Q949V2

UniProtKB/TrEMBL

A0A178WCQ3, A0A5S9U5K5

Conserved Domains (1) summary

cd03761
Location:58 → 245

proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
NM_001332061.1 → NP_001323153.1 20S proteasome beta subunit E1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9U5K5, F4HP14
NM_001198049.1 → NP_001184978.1 20S proteasome beta subunit E1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001184978.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9U5K5, F4HP14

Conserved Domains (2) summary

TIGR03690
Location:57 → 276

20S_bact_beta; proteasome, beta subunit, bacterial type

cd03761
Location:58 → 269

proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...