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    XCP2 xylem cysteine peptidase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838677, updated on 18-Sep-2024

    Summary

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    Official Symbol
    XCP2
    Official Full Name
    xylem cysteine peptidase 2
    Primary source
    TAIR:AT1G20850
    Locus tag
    AT1G20850
    See related
    Araport:AT1G20850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F9H16.17; F9H16_17; PAPAIN-TYPE CYSTEINE ENDOPEPTIDASE XCP2; xylem cysteine peptidase 2
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    Genomic context

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    See XCP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (7252111..7253747)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene multiple chloroplast division site 1 Neighboring gene tonoplast monosaccharide transporter1 Neighboring gene ncRNA Neighboring gene phosphate transporter 1;8 Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cysteine proteases XCP1 and XCP2 aid micro-autolysis within the intact central vacuole during xylogenesis in Arabidopsis roots. Avci U, et al. Plant J, 2008 Oct. PMID 18573193
    2. PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis. Zhang B, et al. Plant J, 2014 Sep. PMID 24947605, Free PMC Article
    3. Cell wall proteins in apoplastic fluids of Arabidopsis thaliana rosettes: identification by mass spectrometry and bioinformatics. Boudart G, et al. Proteomics, 2005 Jan. PMID 15593128
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Stabilization of XCP2 by PRN2 underlies susceptibility to Ralstonia solanacearum in Arabidopsis.
      Title: PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis.
    2. XCP1 and XCP2 function in micro-autolysis within the intact central vacuole before mega-autolysis was initiated by tonoplast implosion. XCP1 has a major role and XCP2 has a minor role in micro-autolysis.
      Title: Cysteine proteases XCP1 and XCP2 aid micro-autolysis within the intact central vacuole during xylogenesis in Arabidopsis roots.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101938.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within programmed cell death involved in cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 

    General protein information

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    Preferred Names
    xylem cysteine peptidase 2
    NP_564126.1
    • xylem cysteine peptidase 2 (XCP2); FUNCTIONS IN: cysteine-type peptidase activity, peptidase activity; INVOLVED IN: proteolysis, developmental programmed cell death; LOCATED IN: cell wall; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C1A, papain (InterPro:IPR013128), Proteinase inhibitor I29, cathepsin propeptide (InterPro:IPR013201), Peptidase C1A, papain C-terminal (InterPro:IPR000668), Peptidase, cysteine peptidase active site (InterPro:IPR000169); BEST Arabidopsis thaliana protein match is: xylem cysteine peptidase 1 (TAIR:AT4G35350.1); Has 7701 Blast hits to 7638 proteins in 709 species: Archae - 59; Bacteria - 219; Metazoa - 3282; Fungi - 4; Plants - 1889; Viruses - 133; Other Eukaryotes - 2115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7252111..7253747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101938.5 → NP_564126.1  xylem cysteine peptidase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564126.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WT15, Q9LM66, Q9SYQ2
      UniProtKB/TrEMBL
      A0A178WGB8, A0A5S9VEW8, A0A7G2DS80
      Conserved Domains (2) summary
      smart00848
      Location:51 → 106
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:138 → 353
      Peptidase_C1; Papain family cysteine protease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LM66.2

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