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    PAB8 poly(A) binding protein 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841399, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAB8
    Official Full Name
    poly(A) binding protein 8
    Primary source
    TAIR:AT1G49760
    Locus tag
    AT1G49760
    See related
    Araport:AT1G49760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14J22.3; F14J22_3; PABP8; poly(A) binding protein 8; POLY(A) BINDING PROTEIN 8
    Summary
    polyadenylate-binding protein, putative / PABP, putative, similar to poly(A)-binding protein GB:AAF66825 GI:7673359 from (Nicotiana tabacum). Highly and ubiquitously expressed. Member of the class II PABP family.
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    Genomic context

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    See PAB8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (18416474..18420111)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PLC-like phosphodiesterases superfamily protein Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ERD15--an attenuator of plant ABA responses and stomatal aperture. Aalto MK, et al. Plant Sci, 2012 Jan. PMID 22118612
    2. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    3. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    4. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001198255.1
    NM_103863.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    poly(A) binding protein 8
    NP_001185184.1
    • poly(A) binding protein 8 (PAB8); CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: poly(A) binding protein 2 (TAIR:AT4G34110.1).
    NP_564554.1
    • poly(A) binding protein 8 (PAB8); FUNCTIONS IN: RNA binding, translation initiation factor activity; INVOLVED IN: response to cadmium ion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: poly(A) binding protein 2 (TAIR:AT4G34110.1); Has 986469 Blast hits to 485112 proteins in 21501 species: Archae - 20784; Bacteria - 581960; Metazoa - 196391; Fungi - 29721; Plants - 62748; Viruses - 68352; Other Eukaryotes - 26513 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18416474..18420111
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198255.1 → NP_001185184.1  poly(A) binding protein 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185184.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FXA2
      UniProtKB/TrEMBL
      A0A178W710, A0A5S9WNH7
      Conserved Domains (1) summary
      TIGR01628
      Location:46 → 646
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

    2. NM_103863.3 → NP_564554.1  poly(A) binding protein 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564554.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FXA2
      UniProtKB/TrEMBL
      A0A178W710, A0A5S9WNH7
      Conserved Domains (1) summary
      TIGR01628
      Location:46 → 646
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FXA2.1

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