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    HEME1 Uroporphyrinogen decarboxylase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820722, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HEME1
    Official Full Name
    Uroporphyrinogen decarboxylase
    Primary source
    TAIR:AT3G14930
    Locus tag
    AT3G14930
    See related
    Araport:AT3G14930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    See HEME1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (5020461..5023146)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rab3 GTPase-activating protein non-catalytic subunit Neighboring gene Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A protein Neighboring gene phosphoenolpyruvate carboxylase 3 Neighboring gene tetratricopetide-repeat thioredoxin-like 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Leaf proteome responses of Arabidopsis thaliana exposed to mild cadmium stress. Semane B, et al. J Plant Physiol, 2010 Mar 1. PMID 20005002
    2. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
    3. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
    4. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112355.3
    NM_180256.2
    NM_202587.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables uroporphyrinogen decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protoporphyrinogen IX biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Uroporphyrinogen decarboxylase
    NP_566495.1
    • HEME1; FUNCTIONS IN: uroporphyrinogen decarboxylase activity; INVOLVED IN: response to cadmium ion; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Uroporphyrinogen decarboxylase HemE (InterPro:IPR006361), Uroporphyrinogen decarboxylase (URO-D) (InterPro:IPR000257); BEST Arabidopsis thaliana protein match is: Uroporphyrinogen decarboxylase (TAIR:AT2G40490.1); Has 7323 Blast hits to 7320 proteins in 2007 species: Archae - 103; Bacteria - 3942; Metazoa - 236; Fungi - 136; Plants - 121; Viruses - 0; Other Eukaryotes - 2785 (source: NCBI BLink).
    NP_850587.1
    • HEME1; FUNCTIONS IN: uroporphyrinogen decarboxylase activity; INVOLVED IN: response to cadmium ion; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Uroporphyrinogen decarboxylase HemE (InterPro:IPR006361), Uroporphyrinogen decarboxylase (URO-D) (InterPro:IPR000257); BEST Arabidopsis thaliana protein match is: Uroporphyrinogen decarboxylase (TAIR:AT2G40490.1); Has 7323 Blast hits to 7320 proteins in 2007 species: Archae - 103; Bacteria - 3942; Metazoa - 236; Fungi - 136; Plants - 121; Viruses - 0; Other Eukaryotes - 2785 (source: NCBI BLink).
    NP_974316.1
    • HEME1; FUNCTIONS IN: uroporphyrinogen decarboxylase activity; INVOLVED IN: response to cadmium ion; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Uroporphyrinogen decarboxylase HemE (InterPro:IPR006361), Uroporphyrinogen decarboxylase (URO-D) (InterPro:IPR000257); BEST Arabidopsis thaliana protein match is: Uroporphyrinogen decarboxylase (TAIR:AT2G40490.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5020461..5023146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180256.2 → NP_850587.1  Uroporphyrinogen decarboxylase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850587.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZB6, Q9LKB1
      UniProtKB/TrEMBL
      A0A5S9XCE5, A0A654FCK6
      Conserved Domains (1) summary
      PLN02433
      Location:62 → 405
      PLN02433; uroporphyrinogen decarboxylase

    2. NM_112355.3 → NP_566495.1  Uroporphyrinogen decarboxylase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566495.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZB6, Q9LKB1
      UniProtKB/TrEMBL
      A0A5S9XCE5, A0A654FCK6
      Conserved Domains (1) summary
      PLN02433
      Location:62 → 405
      PLN02433; uroporphyrinogen decarboxylase

    3. NM_202587.1 → NP_974316.1  Uroporphyrinogen decarboxylase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974316.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VN81, A0A5S9XCE5, A0A654FCK6
      Conserved Domains (1) summary
      PLN02433
      Location:1 → 328
      PLN02433; uroporphyrinogen decarboxylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZB6.2

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